A nuclear chocolate box: the periodic table of nuclear medicine

PJ Blower - Dalton Transactions, 2015 - pubs.rsc.org
Radioisotopes of elements from all parts of the periodic table find both clinical and research
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …

Metal complexes of thiosemicarbazones for imaging and therapy

JR Dilworth, R Hueting - Inorganica Chimica Acta, 2012 - Elsevier
This review gives an account of the coordination chemistry of thiosemicarbazone ligands
with three (tridentate) or four (tetradentate) potential donor atoms. The syntheses and …

Metal-assisted ligand-centered electrocatalytic hydrogen evolution upon reduction of a bis (thiosemicarbazonato) Cu (II) complex

AZ Haddad, SP Cronin, MS Mashuta… - Inorganic …, 2017 - ACS Publications
In this study, we report the electrocatalytic behavior of the neutral, monomeric Cu (II)
complex of diacetyl-bis (N-4-methyl-3-thiosemicarbazonato), CuL1, for metal-assisted ligand …

[HTML][HTML] Assessing tumor hypoxia by positron emission tomography with Cu-ATSM

JP Holland, JS Lewis, F Dehdashti - … ,[and] Section of the Society of …, 2009 - ncbi.nlm.nih.gov
For the last several decades, hypoxia has been recognized to be one of the key factors in
tumor aggression and an important impediment to local and distant control of malignant …

A red-emitting luminescent probe for sequentially detecting Cu2+ and cysteine/histidine in aqueous solution and its imaging application in living zebrafish

Y Yang, Y Li, X Zhi, Y Xu, M Li - Dyes and Pigments, 2020 - Elsevier
A unique red-emissive luminescent probe based on dipicolyl amine (DPA) tethered
ruthenium (II) tris (bipyridine) derivative (Ru-DPA) has been developed for the sequential …

Fluorescent copper (II) bis (thiosemicarbazonates): synthesis, structures, electron paramagnetic resonance, radiolabeling, in vitro cytotoxicity and confocal …

SI Pascu, PA Waghorn, BWC Kennedy… - Chemistry–An Asian …, 2010 - Wiley Online Library
Abstract Copper bis (4‐ethyl‐3‐thiosemicarbazonato) acenaphthenequinone (1) and copper
bis (4‐methyl‐3‐thiosemicarbazonato) acenaphthenequinone (2) are synthesized and …

Use of beta, gamma-unsaturated alpha-ketocarbonyls for a totally regioselective oxidative multicomponent synthesis of polyfunctionalized pyridines

C Allais, T Constantieux, J Rodriguez - Chemistry-A European Journal, 2009 - hal.science
α-Ketocarbonyls have been shown for the first time to be versatile partners in a Michael
addition promoted oxidative domino three-component reaction under heterogeneous …

Nitroimidazole conjugates of bis (thiosemicarbazonato) 64Cu (II)–Potential combination agents for the PET imaging of hypoxia

PD Bonnitcha, SR Bayly, MBM Theobald… - Journal of inorganic …, 2010 - Elsevier
Combination agents comprising two different pharmacophores with the same biological
target have the potential to show additive or synergistic activity. Bis (thiosemicarbazonato) …

Bis (thiosemicarbazones) as bifunctional chelators for the room temperature 64-copper labeling of peptides

R Hueting, M Christlieb, JR Dilworth, EG Garayoa… - Dalton …, 2010 - pubs.rsc.org
A range of new carboxylate functionalised bis (thiosemicarbazone) ligands and their Cu (II)
complexes have been prepared, fully characterised and radiolabeled in high yield with both …

Basic and practical concepts of radiopharmaceutical purification methods

S Molavipordanjani, V Tolmachev… - Drug Discovery …, 2019 - Elsevier
Highlights•High purity is the most crucial requisite for all the radiopharmaceutical.•For
impure radiopharmaceuticals a proper purification step is unavoidable.•Most of the …