Lyme borreliosis

AC Steere, F Strle, GP Wormser, LT Hu… - Nature reviews Disease …, 2016 - nature.com
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of
the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in …

Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

JD Radolf, MJ Caimano, B Stevenson… - Nature reviews …, 2012 - nature.com
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

Lyme disease: a rigorous review of diagnostic criteria and treatment

AT Borchers, CL Keen, AC Huntley… - Journal of autoimmunity, 2015 - Elsevier
Lyme disease was originally identified in Lyme, Connecticut, based upon an unusual cluster
of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently …

[HTML][HTML] Differences in genotype, clinical features, and inflammatory potential of Borrelia burgdorferi sensu stricto strains from Europe and the United States

T Cerar, F Strle, D Stupica, E Ruzic-Sabljic… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
Borrelia burgdorferi sensu stricto isolates from patients with erythema migrans in Europe
and the United States were compared by genotype, clinical features of infection, and …

Skin manifestations of lyme borreliosis: diagnosis and management

RR Muellegger, M Glatz - American journal of clinical dermatology, 2008 - Springer
Lyme borreliosis is a multisystem infectious disease caused by tick-transmitted spirochetes
of the Borrelia burgdorferi sensu lato complex. The three characteristic cutaneous …

Elevated levels of IL-23 in a subset of patients with post–Lyme disease symptoms following erythema migrans

K Strle, D Stupica, EE Drouin… - Clinical infectious …, 2014 - academic.oup.com
Background. The causes of post-Lyme disease symptoms are unclear. Herein, we
investigated whether specific immune responses were correlated with such symptoms …

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

JC Salazar, S Duhnam-Ems, C La Vake… - PLoS …, 2009 - journals.plos.org
It is widely believed that innate immune responses to Borrelia burgdorferi (Bb) are primarily
triggered by the spirochete's outer membrane lipoproteins signaling through cell surface …

[HTML][HTML] Borrelia burgdorferi RST1 (OspC type A) genotype is associated with greater inflammation and more severe Lyme disease

K Strle, KL Jones, EE Drouin, X Li, AC Steere - The American journal of …, 2011 - Elsevier
Evidence is emerging for differential pathogenicity among Borrelia burgdorferi genotypes in
the United States. By using two linked genotyping systems, ribosomal RNA intergenic …

A prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and on the Åland Islands, Finland (2008–2009)

P Wilhelmsson, L Fryland, P Lindblom, J Sjöwall… - Ticks and tick-borne …, 2016 - Elsevier
Lyme borreliosis (LB) is a common and increasing tick-borne disease in Europe. The risk of
acquiring a Borrelia infection after a tick bite is not fully known. Therefore, we investigated …