The folding of transmembrane proteins into the outer membrane presents formidable challenges to Gram-negative bacteria. These proteins must migrate from the cytoplasm …
L Han, J Zheng, Y Wang, X Yang, Y Liu… - Nature structural & …, 2016 - nature.com
In Gram-negative bacteria, the assembly of β-barrel outer-membrane proteins (OMPs) requires the β-barrel–assembly machinery (BAM) complex. We determined the crystal …
AIC Höhr, C Lindau, C Wirth, J Qiu, DA Stroud, S Kutik… - Science, 2018 - science.org
INTRODUCTION The outer membranes of Gram-negative bacteria, mitochondria, and chloroplasts characteristically contain β-barrel membrane proteins. These proteins contain …
Communication of mitochondria with the rest of the cell requires β-barrel proteins of the outer membrane. All β-barrel proteins are synthesized as precursors in the cytosol and …
SK Aoki, JC Malinverni, K Jacoby… - Molecular …, 2008 - Wiley Online Library
Contact‐dependent growth inhibition (CDI) is a phenomenon by which bacterial cell growth is regulated by direct cell‐to‐cell contact via the CdiA/CdiB two‐partner secretion system …
K Weinhäupl, C Lindau, A Hessel, Y Wang, C Schütze… - Cell, 2018 - cell.com
The exchange of metabolites between the mitochondrial matrix and the cytosol depends on β-barrel channels in the outer membrane and α-helical carrier proteins in the inner …
The bacterial outer membrane (OM) is an exceptional biological structure with a unique composition that contributes significantly to the resiliency of Gram-negative bacteria. Since …
The β-barrel assembly machinery (BAM) complex is an essential component of Escherichia coli that inserts and folds outer membrane proteins (OMPs). The natural antibiotic compound …
DM Walther, D Rapaport, J Tommassen - Cellular and Molecular Life …, 2009 - Springer
Membrane-embedded β-barrel proteins span the membrane via multiple amphipathic β- strands arranged in a cylindrical shape. These proteins are found in the outer membranes of …