We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …

The heparan sulphate proteoglycan agrin is expressed as several isoforms in various
tissues. Agrin is best known as a crucial organizer of postsynaptic differentiation at the …

Basement membranes are cell surface associated extracellular matrices containing
laminins, type IV collagens, nidogens, perlecan, agrin, and other macromolecules …

Formation, differentiation and plasticity of synapses, the specialized cell–cell contacts
through which neurons communicate, all require interactions between pre-and post-synaptic …

Proteoglycans located in basement membranes, the nanostructures underling epithelial and
endothelial layers, are unique in several respects. They are usually large, elongated …

Background: Ischemic heart diseases are leading causes of death and reduced life quality
worldwide. Although revascularization strategies significantly reduce mortality after acute …

The vertebrate neuromuscular junction (NMJ) remains the best‐studied model for
understanding the mechanisms involved in synaptogenesis, due to its relatively large size …

The extracellular matrix is a dynamic repository harboring instructive cues that embody
substantial regulatory dominance over many evolutionarily conserved intracellular activities …

Proteoglycans are composite molecules comprising a protein backbone, ie, the core protein,
with covalently attached glycosaminoglycan chains of distinct chemical types. Most …