Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Roadmap for focused ion beam technologies

K Höflich, G Hobler, FI Allen, T Wirtz, G Rius… - Applied Physics …, 2023 - pubs.aip.org
The focused ion beam (FIB) is a powerful tool for fabrication, modification, and
characterization of materials down to the nanoscale. Starting with the gallium FIB, which was …

Mass spectrometry imaging and integration with other imaging modalities for greater molecular understanding of biological tissues

T Porta Siegel, G Hamm, J Bunch, J Cappell… - Molecular imaging and …, 2018 - Springer
Over the last two decades, mass spectrometry imaging (MSI) has been increasingly
employed to investigate the spatial distribution of a wide variety of molecules in complex …

Multimodal imaging mass spectrometry: next generation molecular mapping in biology and medicine

EK Neumann, KV Djambazova… - Journal of the …, 2020 - ACS Publications
Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

Correlated multimodal imaging in life sciences: expanding the biomedical horizon

A Walter, P Paul-Gilloteaux, B Plochberger, L Sefc… - Frontiers in …, 2020 - frontiersin.org
The frontiers of bioimaging are currently being pushed toward the integration and correlation
of several modalities to tackle biomedical research questions holistically and across multiple …

SIMS imaging in neurobiology and cell biology

P Agüi-Gonzalez, S Jähne, NTN Phan - Journal of Analytical Atomic …, 2019 - pubs.rsc.org
Secondary ion mass spectrometry (SIMS) has been increasingly recognized as a powerful
technique for visualizing molecular architectures in the fields of neurobiology and cell …

Hydriding of titanium: Recent trends and perspectives in advanced characterization and multiscale modeling

Y Zhu, TW Heo, JN Rodriguez, PK Weber, R Shi… - Current Opinion in Solid …, 2022 - Elsevier
Titanium (Ti) and its alloys are attractive for a wide variety of structural and functional
applications owing to excellent specific strength, toughness and stiffness, and corrosion …

Imaging and analytics on the helium ion microscope

T Wirtz, O De Castro, JN Audinot… - Annual Review of …, 2019 - annualreviews.org
The helium ion microscope (HIM) has emerged as an instrument of choice for patterning,
imaging and, more recently, analytics at the nanoscale. Here, we review secondary electron …

Chemical analysis of single cells

PE Oomen, MA Aref, I Kaya, NTN Phan… - Analytical …, 2018 - ACS Publications
Heterogeneity in cell populations is a phenomenon encountered in virtually all biological
systems, in whole tissues and cell cultures and from bacterial to mammalian cells. Moreover …