Molecular mechanisms of exercise contributing to tissue regeneration

J Chen, R Zhou, Y Feng, L Cheng - Signal Transduction and Targeted …, 2022 - nature.com
Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements

RM Dorrian, CF Berryman, A Lauto… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …

Effect of various exercise regimens on selected exercise-induced cytokines in healthy people

R Domin, D Dadej, M Pytka, A Zybek-Kocik… - International Journal of …, 2021 - mdpi.com
Different forms of physical activity—endurance, resistance or dynamic power—stimulate
cytokine release from various tissues to the bloodstream. Receptors for exercise-induced …

Neural stem cells in the adult spinal cord

H Sabelström, M Stenudd, J Frisén - Experimental neurology, 2014 - Elsevier
Spinal cord injury results in cell loss, disruption of neural circuitry and chronic functional
impairment. Several different cell types generate progeny in response to injury, which …

Brain-derived neurotrophic factor: Regulation, effects, and potential clinical relevance

EE Benarroch - Neurology, 2015 - AAN Enterprises
Brain-derived neurotrophic factor (BDNF) is the most ubiquitous and intensively studied
member of the family of neurotrophins in the CNS. The transcriptional regulation of BDNF is …

Recent advances in nanotherapeutic strategies for spinal cord injury repair

YH Song, NK Agrawal, JM Griffin, CE Schmidt - Advanced drug delivery …, 2019 - Elsevier
Spinal cord injury (SCI) is a devastating and complicated condition with no cure available.
The initial mechanical trauma is followed by a secondary injury characterized by …

Cell-seeded alginate hydrogel scaffolds promote directed linear axonal regeneration in the injured rat spinal cord

MI Günther, N Weidner, R Müller, A Blesch - Acta Biomaterialia, 2015 - Elsevier
Despite recent progress in enhancing axonal growth in the injured spinal cord, the guidance
of regenerating axons across an extended lesion site remains a major challenge. To …

Predictors of 5 year survival rate in hepatocellular carcinoma patients

A Sarveazad, S Agah, A Babahajian… - Journal of Research …, 2019 - journals.lww.com
Background: Hepatocellular carcinoma (HCC) is one of the most common primary hepatic
malignancies and growing challenges of global health. In this study, for the first time in Iran …

Exercise-induced plasticity in signaling pathways involved in motor recovery after spinal cord injury

JN Bilchak, G Caron, MP Côté - International journal of molecular …, 2021 - mdpi.com
Spinal cord injury (SCI) leads to numerous chronic and debilitating functional deficits that
greatly affect quality of life. While many pharmacological interventions have been explored …

The linear-ordered collagen scaffold-BDNF complex significantly promotes functional recovery after completely transected spinal cord injury in canine

S Han, B Wang, W Jin, Z Xiao, X Li, W Ding, M Kapur… - Biomaterials, 2015 - Elsevier
Spinal cord injury (SCI) is still a worldwide clinical challenge for which there is no viable
therapeutic method. We focused on developing combinatorial methods targeting the …