[HTML][HTML] Iron in infection and immunity

M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

Oxidative stress and pathogenesis in malaria

M Vasquez, M Zuniga, A Rodriguez - Frontiers in cellular and …, 2021 - frontiersin.org
Malaria is a highly inflammatory and oxidative disease. The production of reactive oxygen
species by host phagocytes is an essential component of the host response to Plasmodium …

“Asymptomatic” malaria: a chronic and debilitating infection that should be treated

I Chen, SE Clarke, R Gosling, B Hamainza… - PLoS …, 2016 - journals.plos.org
“Asymptomatic” Malaria: A Chronic and Debilitating Infection That Should Be Treated | PLOS
Medicine Skip to main content Advertisement PLOS Medicine Browse Current Issue Journal …

Innate sensing of malaria parasites

RT Gazzinelli, P Kalantari, KA Fitzgerald… - Nature Reviews …, 2014 - nature.com
Innate immune receptors have a key role in immune surveillance by sensing
microorganisms and initiating protective immune responses. However, the innate immune …

Heme on innate immunity and inflammation

FF Dutra, MT Bozza - Frontiers in pharmacology, 2014 - frontiersin.org
Heme is an essential molecule expressed ubiquitously all through our tissues. Heme plays
major functions in cellular physiology and metabolism as the prosthetic group of diverse …

Malaria: what's new in the management of malaria?

K Plewes, SJ Leopold, HWF Kingston… - Infectious Disease …, 2019 - id.theclinics.com
Malaria affected an estimated 216 million people causing 445,000 deaths in 2016. 1 This
reduced burden of disease and death is a result of more than a century of worldwide effort …

Oxidative stress in malaria: potential benefits of antioxidant therapy

ARQ Gomes, N Cunha, ELP Varela… - International Journal of …, 2022 - mdpi.com
Malaria is an infectious disease and a serious public health problem in the world, with 3.3
billion people in endemic areas in 100 countries and about 200 million new cases each …

The influence of parasite infections on host immunity to co-infection with other pathogens

NA Mabbott - Frontiers in immunology, 2018 - frontiersin.org
Parasites have evolved a wide range of mechanisms that they use to evade or manipulate
the host's immune response and establish infection. The majority of the in vivo studies that …

New insights into malaria pathogenesis

CA Moxon, MP Gibbins, D McGuinness… - Annual Review of …, 2020 - annualreviews.org
Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

SL Knackstedt, A Georgiadou, F Apel… - Science …, 2019 - science.org
Neutrophils are essential innate immune cells that extrude chromatin in the form of
neutrophil extracellular traps (NETs) when they die. This form of cell death has potent …