Highlights•Review of the present status of the development of antimicrobial peptides
(AMPs).•Recent advances in designing new anti-infective agents with enhanced …

Neurodegenerative diseases are relentlessly progressive, severely impacting affected
patients, families and society as a whole. Increased life expectancy has made these …

There has recently been great concern regarding antibiotics due to potential drug resistance
and the impact of antibiotics on the environment. Antimicrobial peptides are believed to have …

Biologically active peptides have been attracting increasing attention, whether to improve
the understanding of their mechanisms of action or in the search for new therapeutic drugs …

Mastoparan is a typical cationic and amphipathic tetradecapeptide found in wasp venom
and exhibits potent biological activities. Yet, compared with other insect-derived peptides …

Wasps, members of the order Hymenoptera, are distributed in different parts of the world,
including Brazil, Thailand, Japan, Korea, and Argentina. The lifestyles of the wasps are …

The emergence of antibiotic-resistant clinical isolates and the decreased rate of
development of new antibiotics are a constant threat to human health. In this context, the …

A series of hybrid peptides were designed by connecting an antimicrobial peptide Ce (1–8)
with a lipopolysaccharide (LPS)-targeting peptide Lf (28–34) via different linkers …

The emergence of multidrug-resistant bacteria has dramatically increased the lethality, level
of resistance, and difficulty of treatment. In this study, a series of new antimicrobial peptides …

Anti-cancer peptides (ACPs) are small cationic and hydrophobic peptides that are more toxic
to cancer cells than normal cells. ACPs kill cancer cells by causing irreparable membrane …