Comprehensive review of targeted therapy for colorectal cancer

YH Xie, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …

Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial

D Morton, M Seymour, L Magill, K Handley… - Journal of clinical …, 2023 - ascopubs.org
PURPOSE Neoadjuvant chemotherapy (NAC) has potential advantages over standard
postoperative chemotherapy for locally advanced colon cancer but requires formal …

ctDNA and adjuvant therapy for colorectal cancer: time to re-invent our treatment paradigm

M Naidoo, P Gibbs, J Tie - Cancers, 2021 - mdpi.com
Simple Summary There is currently a lack of useful tests to detect microscopic residual
disease in patients who have undergone surgery to remove their bowel cancer. This inability …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer

JD Vogel, SI Felder, AR Bhama… - Diseases of the Colon …, 2022 - journals.lww.com
METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …

[HTML][HTML] Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

G Argilés, J Tabernero, R Labianca, D Hochhauser… - Annals of …, 2020 - Elsevier
Colorectal cancer (CRC) is the third most common tumour in men and the second in women,
accounting for 10% of all tumour types worldwide. Incidence is 25% higher in males and …

Adoption of total neoadjuvant therapy for locally advanced rectal cancer

A Cercek, CSD Roxburgh, P Strombom, JJ Smith… - JAMA …, 2018 - jamanetwork.com
Importance Treatment of locally advanced rectal (LARC) cancer involves chemoradiation,
surgery, and chemotherapy. The concept of total neoadjuvant therapy (TNT), in which …

A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a …

A Kleppe, OJ Skrede, S De Raedt, TS Hveem… - The lancet …, 2022 - thelancet.com
Summary Background The DoMore-v1-CRC marker was recently developed using deep
learning and conventional haematoxylin and eosin-stained tissue sections, and was …

S3-leitlinie–kolorektales karzinom

W Schmiegel, B Buchberger… - Zeitschrift für …, 2017 - thieme-connect.com
2.1 Geltungsbereich und Zweck 2.1. 1. Zielsetzung und Fragestellung Das Kolorektale
Karzinom (KRK) ist mit etwa 64 000 Neuerkrankungen und ca. 26 000 Todesfällen pro Jahr …

Pre-and postoperative capecitabine without or with oxaliplatin in locally advanced rectal cancer: PETACC 6 trial by EORTC GITCG and ROG, AIO, AGITG, BGDO, and …

HJ Schmoll, A Stein, E Van Cutsem, T Price… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The PETACC 6 trial investigates whether the addition of oxaliplatin to
preoperative capecitabine-based chemoradiation and postoperative capecitabine improves …

Three versus 6 months of oxaliplatin-based adjuvant chemotherapy for patients with stage III colon cancer: disease-free survival results from a randomized, open-label …

T André, D Vernerey, L Mineur, J Bennouna… - Journal of clinical …, 2018 - ascopubs.org
Purpose Reduction of adjuvant treatment duration may decrease toxicities without loss of
efficacy in stage III colon cancer. This could offer clear advantages to patients and health …