[HTML][HTML] Current status of sorafenib nanoparticle delivery systems in the treatment of hepatocellular carcinoma

FH Kong, QF Ye, XY Miao, X Liu, SQ Huang, L Xiong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the
leading causes of cancer-related death worldwide. Advanced HCC displays strong …

Amphiphilic block copolymers in drug delivery: Advances in formulation structure and performance

AM Bodratti, P Alexandridis - Expert opinion on drug delivery, 2018 - Taylor & Francis
Introduction: Nanostructured delivery vehicles can address key challenges facing drug
delivery, including the lipophilic nature of therapeutic compounds and their effective …

The role of photoactivated and non-photoactivated verteporfin on tumor

C Wei, X Li - Frontiers in pharmacology, 2020 - frontiersin.org
Verteporfin (VP) has long been clinically used to treat age-related macular degeneration
(AMD) through photodynamic therapy (PDT). Recent studies have reported a significant anti …

[HTML][HTML] An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

MQ Mesquita, CJ Dias, S Gamelas… - Anais da Academia …, 2018 - SciELO Brasil
Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are
destroyed by reactive oxygen species (ROS) produced by photosensitizers following its …

Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications

I Jarak, CL Varela, ET da Silva, FFM Roleira… - European Journal of …, 2020 - Elsevier
Pluronics are a class of amphiphilic tri-block copolymers with wide pharmaceutical
applicability. In the past decades, the ability to form biocompatible nanosized micelles was …

Red-light-photosensitized NO release and its monitoring in cancer cells with biodegradable polymeric nanoparticles

A Fraix, C Parisi, G Longobardi, C Conte… - …, 2023 - ACS Publications
The role of nitric oxide (NO) as an “unconventional” therapeutic and the strict dependence of
biological effects on its concentration require the generation of NO with precise …

Delivery of thymoquinone through hyaluronic acid-decorated mixed Pluronic® nanoparticles to attenuate angiogenesis and metastasis of triple-negative breast cancer

S Bhattacharya, A Ghosh, S Maiti, M Ahir… - Journal of Controlled …, 2020 - Elsevier
Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic subtype of
breast cancer showing non-responsiveness to most available therapeutic options …

Aptamer-mediated hollow MnO2 for targeting the delivery of sorafenib

Z Wang, C Wu, J Liu, S Hu, J Yu, Q Yin, H Tian… - Drug Delivery, 2023 - Taylor & Francis
Sorafenib (SRF) presents undesirable effects in clinical treatment, due to the lack of
targeting, poor water solubility, and obvious side effects. In this study, we constructed a …

Targeted and synergic glioblastoma treatment: multifunctional nanoparticles delivering verteporfin as adjuvant therapy for temozolomide chemotherapy

DS Pellosi, LB Paula, MT de Melo… - Molecular …, 2019 - ACS Publications
Despite advances in cancer therapies, glioblastoma multiforme treatment remains inefficient
due to the brain–blood barrier (BBB) inhibitory activity and to the low temozolomide (TMZ) …

Strategies for optimizing the delivery to tumors of macrocyclic photosensitizers used in photodynamic therapy (PDT)

F Moret, E Reddi - Journal of Porphyrins and Phthalocyanines, 2017 - World Scientific
This review briefly summaries the principles and mechanisms of action of photodynamic
therapy (PDT) as concerns its application in the oncological field, highlighting its drawbacks …