Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …

Several techniques to assisting in the drug design and discovery stages have been
developed during the last several decades. The bulk of these techniques aimed to find novel …

Extensive research into prodrug modification of active pharmaceutical ingredients and
nanoparticle drug delivery systems has led to unprecedented levels of control over the …

Azo dyes are widely used in textile, fiber, cosmetic, leather, paint and printing industries.
Besides their characteristic coloring function, azo compounds are reported as antibacterial …

Despite the exceptional performance of recyclable biphasic pretreatment systems (ie, p-
toluenesulfonic acid (TsOH)/pentanol, H 2 SO 4/butanol, and AlCl 3/MTHF) in the holistic …

This review provides the reader a concise overview of the majority of prodrug approaches
with the emphasis on the modern approaches to prodrug design. The chemical approach …

Enzyme-activated prodrug therapy (EAPT) is a widely-used and effective treatment method
for cancer by converting prodrugs into drugs at the demanded time and space, whose key …

The palatability of the active ingredient of a drug is a significant obstacle in developing a
patient friendly dosage form. Organoleptic properties, such as taste, are an important factor …

Prodrugs are designed to improve pharmaceutical/biopharmaceutical characteristics,
pharmacokinetic/pharmacodynamic properties, site-specificity, and more. A crucial step in …