Neonatal morbidities of fetal growth restriction: pathophysiology and impact

A Malhotra, BJ Allison, M Castillo-Melendez… - Frontiers in …, 2019 - frontiersin.org
Being born small lays the foundation for short-term and long-term implications for life.
Intrauterine or fetal growth restriction describes the pregnancy complication of pathological …

Regulation of the pulmonary circulation in the fetus and newborn

Y Gao, JU Raj - Physiological reviews, 2010 - journals.physiology.org
During the development of the pulmonary vasculature in the fetus, many structural and
functional changes occur to prepare the lung for the transition to air breathing. The …

Bronchopulmonary dysplasia: where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease

B Thébaud, SH Abman - American journal of respiratory and critical …, 2007 - atsjournals.org
Bronchopulmonary dysplasia and emphysema are significant global health problems at the
extreme stages of life. Both are characterized by arrested alveolar development or loss of …

Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury …

B Thébaud, F Ladha, ED Michelakis, M Sawicka… - Circulation, 2005 - Am Heart Assoc
Background—Bronchopulmonary dysplasia (BPD) and pulmonary emphysema, both
significant global health problems, are characterized by a loss of alveoli. Vascular …

Development and pathology of the hyaloid, choroidal and retinal vasculature

M Saint-Geniez, PA D'Amore - The International journal of …, 2004 - dash.harvard.edu
During embryogenesis, the development and differentiation of the eye requires the
concomitant formation of the neural/glial elements along with a dense vascular network. The …

Pulmonary hypertension and vascular abnormalities in bronchopulmonary dysplasia

PM Mourani, SH Abman - Clinics in perinatology, 2015 - perinatology.theclinics.com
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in preterm infants
who require mechanical ventilation and oxygen therapy for postnatal respiratory distress. 1 …

Regulation of angiogenesis by extracellular matrix

J Sottile - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2004 - Elsevier
During angiogenesis, endothelial cell growth, migration, and tube formation are regulated by
pro-and anti-angiogenic factors, matrix-degrading proteases, and cell–extracellular matrix …

Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia

KR Stenmark, SH Abman - Annu. Rev. Physiol., 2005 - annualreviews.org
▪ Abstract Past studies have primarily focused on how altered lung vascular growth and
development contribute to pulmonary hypertension. Recently, basic studies of vascular …

Pulmonary vascular disease in bronchopulmonary dysplasia: pulmonary hypertension and beyond

PM Mourani, SH Abman - Current opinion in pediatrics, 2013 - journals.lww.com
Despite many recent advances, PVD remains an important contributor to poor outcomes in
preterm infants with BPD. Substantial challenges persist, especially with regard to …

Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia

J Bourbon, O Boucherat, B Chailley-Heu… - Pediatric research, 2005 - nature.com
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in very premature
infants and is characterized by impaired alveologenesis. This ultimate phase of lung …