Hemolymph of molluscan origin: from biochemistry to modern biomaterials science

T Machałowski, T Jesionowski - Applied Physics A, 2021 - Springer
Molluscan hemolymph is a unique kind of body fluid, which in many respects is analogous to
human blood, although there are several crucial differences. Here, for the first time, we …

Perfusion drugs for non‑muscle invasive bladder cancer

J Qian, Q Zhang, Y Cao, X Chu, Y Gao… - Oncology …, 2024 - spandidos-publications.com
The high recurrence rate and poor prognosis of non‑muscle invasive bladder cancer (BC)
are challenges that need to be urgently addressed. Transurethral cystectomy for bladder …

An 1H NMR- and MS-Based Study of Metabolites Profiling of Garden Snail Helix aspersa Mucus

NG Vassilev, SD Simova, M Dangalov, L Velkova… - Metabolites, 2020 - mdpi.com
Metabolic profiling based on 1H nuclear magnetic resonance (NMR) spectroscopy was
applied with the aim to investigate the functional role of the metabolites in lyophilized mucus …

The effect of biologically active compounds in the mucus of slugs Limax maximus and Arion rufus on human skin cells

A Leśków, M Tarnowska, I Szczuka, D Diakowska - Scientific Reports, 2021 - nature.com
Molluscs are one of the sources of biologically active substances, which are now intensively
studied, especially for their anti-cancer properties. Malignant melanoma originates from …

Antitumor Activity of Bioactive Compounds from Rapana venosa against Human Breast Cell Lines

M Petrova, Z Vlahova, M Schröder, J Todorova… - Pharmaceuticals, 2023 - mdpi.com
This study is the first report describing the promising antitumor activity of biologically active
compounds isolated from the hemolymph of marine snail Rapana venosa—a fraction with …

Hemocyanins from Helix and Rapana Snails Exhibit in Vitro Antitumor Effects in Human Colorectal Adenocarcinoma

A Georgieva, K Todorova, I Iliev, V Dilcheva, I Vladov… - Biomedicines, 2020 - mdpi.com
Hemocyanins are oxygen-transporting glycoproteins in the hemolymph of arthropods and
mollusks that attract scientific interest with their diverse biological activities and potential …

Effect of extracts from eggs of Helix aspersa maxima and Helix aspersa aspersa snails on Caco-2 colon cancer cells

M Matusiewicz, K Marczak, B Kwiecińska, J Kupis… - PeerJ, 2022 - peerj.com
Background Colorectal cancer is the third most commonly diagnosed cancer. Natural
compounds, administered together with conventional chemotherapeutic agent (s) and/or …

Purification, characterization and biological functions of metalloprotein isolated from haemolymph of mud crab Scylla serrata (Forskal, 1775)

KR Durairaj, K Saravanan, K Mohan… - International Journal of …, 2020 - Elsevier
In recent years, an enormous number of naturally occurring biological macromolecules has
been reported worldwide due to its antibacterial and anticancerous potential. Among them …

Assessment of the In Vitro and In Vivo Antitumor Activity of Hemocyanins from Helix aspersa, Helix lucorum, and Rapana venosa in a Graffi Myeloid Tumor Model

A Georgieva, K Todorova, I Iliev, V Dilcheva, I Vladov… - Biomedicines, 2023 - mdpi.com
Hemocyanins are oxygen-transporting glycoproteins in the hemolymph of some invertebrate
species that attracted scientific interest as potential anticancer agents. The present study …

Antitumour activity of different bioactive compounds from hemolymph and mucus of Mollusca against human urinary bladder cancer cell lines

M Nikolova, S Konstantinov, L Velkova… - Proceedings of the …, 2022 - proceedings.bas.bg
In this study, we isolated different bioactive compounds and fractions from Rapana venosa
(RvH), Helix aspersa (HaH) and Helix lucorum (HlH) and then we evaluated their in vitro …