The role of genetic and epigenetic factors in tumor initiation and progression is well
documented. Histone deacetylases (HDACs), histone methyl transferases (HMTs), and DNA …

Bladder cancer is one of the most common malignancies in the world. Cisplatin is one of the
most potent and widely used anticancer drugs and has been employed in several …

Dysregulation of histone deacetylases (HDACs) is closely related to tumor development and
progression. As promising anticancer targets, HDACs have gained a great deal of research …

Abstract Histone deacetylase 8 (HDAC8) aberrantly deacetylates histone and non-histone
proteins. These include structural maintenance of chromosome 3 (SMC3) cohesin protein …

Background Epigenetic alterations are known contributors to cancer development and
aggressiveness. Additional to alterations in cancer cells, aberrant epigenetic marks are …

In most bladder cancer (BC) patients, cancer cells will eventually develop chemical
resistance causing increased mortality. This study aimed to explore the mechanism of …

Simple Summary Human papillomavirus (HPV) infection is a highly prevalent sexually
transmitted disease globally. Although most HPV infections do not result in cancer, certain …

Histone deacetylases (HDACs) have long been implicated in tumorigenesis and tumor
progression demonstrating their important participation in neoplasia. Therefore, numerous …

Simple Summary Histone deacetylases (HDACs) are enzymes that control gene expression
and are involved in the onset of serious human pathologies, including cancer; hence, their …

Epigenetic regulation is an important layer of transcriptional control with the particularity to
affect the broad spectrum of genome. Over the years, largely due to the substantial number …