[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

Cell membrane-derived nanomaterials for biomedical applications

RH Fang, Y Jiang, JC Fang, L Zhang - Biomaterials, 2017 - Elsevier
The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation

O Koniev, A Wagner - Chemical Society Reviews, 2015 - pubs.rsc.org
Bioconjugation methodologies have proven to play a central enabling role in the recent
development of biotherapeutics and chemical biology approaches. Recent endeavours in …

Recent advances and remaining challenges for polymeric nanocomposites in healthcare applications

S Kumar, M Nehra, N Dilbaghi, K Tankeshwar… - Progress in polymer …, 2018 - Elsevier
Remarkable advancements in material technologies have accelerated the use of many new
materials and their hybrids and composites in diverse applications. Among such available …

Synthesis of Porous Fe3O4 Nanospheres and Its Application for the Catalytic Degradation of Xylenol Orange

M Zhu, G Diao - The Journal of Physical Chemistry C, 2011 - ACS Publications
Porous magnetite (Fe3O4) nanospheres composed of primary nanocrystals have been
successfully synthesized by solvothermal method with FeCl3· 6H2O serving as the single …

A smart platform for hyperthermia application in cancer treatment: cobalt-doped ferrite nanoparticles mineralized in human ferritin cages

E Fantechi, C Innocenti, M Zanardelli, M Fittipaldi… - ACS …, 2014 - ACS Publications
Magnetic nanoparticles, MNPs, mineralized within a human ferritin protein cage, HFt, can
represent an appealing platform to realize smart therapeutic agents for cancer treatment by …

Polymeric multifunctional nanomaterials for theranostics

H Peng, X Liu, G Wang, M Li, KM Bratlie… - Journal of Materials …, 2015 - pubs.rsc.org
Nanocarriers provide a platform to integrate therapy and diagnostics, which is an emerging
direction in medical practice. Beyond simply therapeutic functionality, theranostic …

[HTML][HTML] Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery

SK Yen, P Padmanabhan, ST Selvan - Theranostics, 2013 - ncbi.nlm.nih.gov
In recent years, multifunctional nanoparticles (NPs) consisting of either metal (eg Au), or
magnetic NP (eg iron oxide) with other fluorescent components such as quantum dots (QDs) …

Engineering iron oxide nanoparticles for clinical settings

AL Cortajarena, D Ortega, SM Ocampo… - …, 2014 - journals.sagepub.com
Iron oxide nanoparticles (IONPs) occupy a privileged position among magnetic
nanomaterials with potential applications in medicine and biology. They have been widely …

Antibody–drug conjugates: Targeting melanoma with cisplatin encapsulated in protein-cage nanoparticles based on human ferritin

E Falvo, E Tremante, R Fraioli, C Leonetti, C Zamparelli… - Nanoscale, 2013 - pubs.rsc.org
A novel antibody–drug conjugate (ADC) was synthesized incorporating ferritin-based
nanoparticles. An average of three molecules of monoclonal antibody (mAb) Ep1 to the …