Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

S Bandari, D Nyavanandi, N Dumpa… - Advanced drug delivery …, 2021 - Elsevier
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …

Melt extrusion with poorly soluble drugs–An integrated review

MA Repka, S Bandari, VR Kallakunta, AQ Vo… - International journal of …, 2018 - Elsevier
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …

Hot melt extrusion: Highlighting physicochemical factors to be investigated while designing and optimizing a hot melt extrusion process

R Censi, MR Gigliobianco, C Casadidio, P Di Martino - Pharmaceutics, 2018 - mdpi.com
Hot-melt extrusion (HME) is a well-accepted and extensively studied method for preparing
numerous types of drug delivery systems and dosage forms. It offers several advantages: no …

Application of surfactants in solid dispersion technology for improving solubility of poorly water soluble drugs

SP Chaudhari, RP Dugar - Journal of drug delivery science and technology, 2017 - Elsevier
Discovery of several poorly water soluble drugs in the past decade has led to the constant
need of developing a novel dosage form which increases the solubility of these drug. They …

Influence of polysaccharide as co-encapsulant on powder characteristics, survival and viability of microencapsulated Lactobacillus paracasei Lpc-37 by spray drying

T Tao, Z Ding, D Hou, S Prakash, Y Zhao, Z Fan… - Journal of Food …, 2019 - Elsevier
In the present work, five polysaccharides were selected as co-encapsulant of skim milk
based matrix and used for the microencapsulation of Lactobacillus paracasei Lpc-37 by …

[HTML][HTML] Formulation and characterization of lornoxicam-loaded cellulosic-microsponge gel for possible applications in arthritis

Y He, K Majid, M Maqbool, T Hussain… - Saudi Pharmaceutical …, 2020 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease associated with severe joint pain.
Herein, we report lornoxicam loaded cellulosic microsponge gel formulation with sustained …

An update on the contribution of hot-melt extrusion technology to novel drug delivery in the twenty-first century: part I

VR Kallakunta, S Sarabu, S Bandari… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Currently, hot melt extrusion (HME) is a promising technology in the
pharmaceutical industry, as evidenced by its application to manufacture various FDA …

Development and Characterization of Eudragit® EPO-Based Solid Dispersion of Rosuvastatin Calcium to Foresee the Impact on Solubility, Dissolution and …

S Inam, M Irfan, NUA Lali, H Khalid Syed, S Asghar… - Pharmaceuticals, 2022 - mdpi.com
Poor solubility is the major challenge involved in the formulation development of new
chemical entities (NCEs), as more than 40% of NCEs are practically insoluble in water. Solid …

[HTML][HTML] Development and evaluation of lafutidine solid dispersion via hot melt extrusion: Investigating drug-polymer miscibility with advanced characterisation

R Fule, P Amin - asian journal of pharmaceutical sciences, 2014 - Elsevier
In current study, immediate release solid dispersion (SD) formulation of antiulcer drug
lafutidine (LAFT) was developed using hot melt extrusion (HME) technique. Amphiphilic …

The advent of a novel manufacturing technology in pharmaceutics: Superiority of fused deposition modeling 3D printer

Y Joo, I Shin, G Ham, SM Abuzar, SM Hyun… - Journal of …, 2020 - Springer
Abstract Background Three-dimensional (3D) printing is a process for creating 3D objects
with various geometries using digital modeling, and it is widely used in the construction and …