Common features of enveloped viruses and implications for immunogen design for next-generation vaccines
FA Rey, SM Lok - Cell, 2018 - cell.com
Enveloped viruses enter cells by inducing fusion of viral and cellular membranes, a process
catalyzed by a specialized membrane-fusion protein expressed on their surface. This review …
catalyzed by a specialized membrane-fusion protein expressed on their surface. This review …
Glycosylation of viral proteins: Implication in virus–host interaction and virulence
T Feng, J Zhang, Z Chen, W Pan, Z Chen, Y Yan, J Dai - Virulence, 2022 - Taylor & Francis
Glycans are among the most important cell molecular components. However, given their
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
Y Wu, F Wang, C Shen, W Peng, D Li, C Zhao, Z Li, S Li… - Science, 2020 - science.org
Neutralizing antibodies could potentially be used as antivirals against the coronavirus
disease 2019 (COVID-19) pandemic. Here, we report isolation of four human-origin …
disease 2019 (COVID-19) pandemic. Here, we report isolation of four human-origin …
[HTML][HTML] Lrp1 is a host entry factor for Rift Valley fever virus
Rift Valley fever virus (RVFV) is a zoonotic pathogen with pandemic potential. RVFV entry is
mediated by the viral glycoprotein (Gn), but host entry factors remain poorly defined. Our …
mediated by the viral glycoprotein (Gn), but host entry factors remain poorly defined. Our …
CCR2 is a host entry receptor for severe fever with thrombocytopenia syndrome virus
L Zhang, X Peng, Q Wang, J Li, S Lv, S Han… - Science …, 2023 - science.org
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne
bunyavirus causing a high fatality rate of up to 30%. To date, the receptor mediating SFTSV …
bunyavirus causing a high fatality rate of up to 30%. To date, the receptor mediating SFTSV …
Cryo-EM structure of severe fever with thrombocytopenia syndrome virus
The severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne human-
infecting bunyavirus, which utilizes two envelope glycoproteins, Gn and Gc, to enter host …
infecting bunyavirus, which utilizes two envelope glycoproteins, Gn and Gc, to enter host …
Rift Valley fever: biology and epidemiology
D Wright, J Kortekaas, TA Bowden… - Journal of General …, 2019 - microbiologyresearch.org
Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that was first discovered in Kenya
in 1930 and is now endemic throughout multiple African countries and the Arabian …
in 1930 and is now endemic throughout multiple African countries and the Arabian …
Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses
NS Chapman, RJG Hulswit, JLB Westover… - Nature …, 2023 - nature.com
Abstract The zoonotic Rift Valley fever virus (RVFV) can cause severe disease in humans
and has pandemic potential, yet no approved vaccine or therapy exists. Here we describe a …
and has pandemic potential, yet no approved vaccine or therapy exists. Here we describe a …
The hantavirus surface glycoprotein lattice and its fusion control mechanism
Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks worldwide for
which no treatment is available. Hantavirus particles are pleomorphic and display a …
which no treatment is available. Hantavirus particles are pleomorphic and display a …
A highly potent human neutralizing antibody prevents vertical transmission of Rift Valley fever virus in a rat model
CM McMillen, NS Chapman, RM Hoehl… - Nature …, 2023 - nature.com
Rift Valley fever virus (RVFV) is an emerging mosquito-transmitted virus that circulates in
livestock and humans in Africa and the Middle East. Outbreaks lead to high rates of …
livestock and humans in Africa and the Middle East. Outbreaks lead to high rates of …