Many pathogens are able to manipulate the signaling pathways responsible for the
generation of host immune responses. Here we examine and model a respiratory infection …

We present schema redescription as a methodology to characterize canalization in
automata networks used to model biochemical regulation and signalling. In our formulation …

Motivation Cellular behavior is determined by complex non-linear interactions between
numerous intracellular molecules that are often represented by Boolean network models. To …

Down syndrome (DS) is caused by trisomy of chromosome 21. All individuals with DS exhibit
some level of cognitive dysfunction. It is generally accepted that these abnormalities are a …

Canalization of genetic regulatory networks has been argued to be favoured by evolutionary
processes due to the stability that it can confer to phenotype expression. We explore …

Understanding design principles of molecular interaction networks is an important goal of
molecular systems biology. Some insights have been gained into features of their network …

(54) METHODS OF PRODUCING RPE CELLS AND (60) Provisional application No.
60/998,668, filed on Oct. COMPOSITIONS OF RIPE CELLS 12, 2007, provisional application …

Colorectal tumors originate and develop within intestinal crypts. Even though some of the
essential phenomena that characterize crypt structure and dynamics have been effectively …

Consider a large Boolean network with a feed forward structure. Given a probability
distribution on the inputs, can one find, possibly small, collections of input nodes that …

Motivation: Modern experimental techniques for time course measurement of gene
expression enable the identification of dynamical models of genetic regulatory networks. In …