Periodontal disease: A systemic condition

GEM Villoria, RG Fischer, EMB Tinoco… - Periodontology …, 2024 - Wiley Online Library
For decades, periodontitis has been considered to be a local inflammatory disease of the
periodontal tissues in the oral cavity. Initially, associations of periodontitis with a multitude of …

Inflammation indices in association with periodontitis and cancer

KA Walther, S Gröger, JAH Vogler… - Periodontology …, 2024 - Wiley Online Library
Inflammation is a complex physiological process that plays a pivotal role in many if not all
pathological conditions, including infectious as well as inflammatory diseases, like …

J‐shaped association between systemic immune‐inflammation index and periodontitis: Results from NHANES 2009–2014

R Cao, C Li, F Geng, Y Pan - Journal of Periodontology, 2024 - Wiley Online Library
Background To examine the relationship between the systemic immune‐inflammation index
(SII) and periodontitis and to investigate possible effect modifiers. Methods Data used in the …

Inflammation of the periodontium associates with risk of future cardiovascular events

TE Van Dyke, KE Kholy, A Ishai… - Journal of …, 2021 - Wiley Online Library
Background While growing evidence suggests a link between periodontal disease (PD) and
cardiovascular disease (CVD), the independence of this association and the pathway …

Unexpected relationships: Periodontal diseases: atherosclerosis–plaque destabilization? From the teeth to a coronary event

MR Czerniuk, S Surma, M Romańczyk, JM Nowak… - Biology, 2022 - mdpi.com
Simple Summary Periodontal disease and atherosclerotic cardiovascular disease are very
common around the world. Coronary artery disease is the leading cause of death. The main …

[HTML][HTML] Oral health and atherosclerotic cardiovascular disease: A review

E Gianos, EA Jackson, A Tejpal, K Aspry… - American journal of …, 2021 - Elsevier
Periodontal disease (PD) is common in the US and globally. Evidence suggests that poor
oral health is associated with atherosclerotic cardiovascular disease (ASCVD); however, this …

Periodontitis impacts on thrombotic diseases: from clinical aspect to future therapeutic approaches

J Ge, X Zhu, C Weng, D Yuan, J Zhao, L Zhao… - International Journal of …, 2024 - nature.com
Periodontitis is a chronic inflammatory disease initiated by biofilm microorganisms and
mediated by host immune imbalance. Uncontrolled periodontal infections are the leading …

[HTML][HTML] Single-cell analysis of platelets from patients with periodontitis and diabetes

H Lee, JY Joo, J Kang, Y Yu, YH Kim… - Research and Practice in …, 2023 - Elsevier
Background Blood platelets are known to play a role in the development of atherosclerotic
disease, thrombi, and hemostasis. Investigation of blood platelet transcriptome could …

Glucose and lipid metabolism indexes and blood inflammatory biomarkers of patients with severe periodontitis: a cross‐sectional study

X Guan, X Wang, Y Li, J Xu, L He, L Xu… - Journal of …, 2023 - Wiley Online Library
Background To investigate the relation of established glucose and lipid metabolism indexes
and blood inflammatory biomarkers with severe periodontitis in systemically healthy …

Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis

V Senini, U Amara, M Paul, H Kim - Journal of Periodontology, 2019 - Wiley Online Library
Background Periodontitis confers an increased risk for cardiovascular diseases, including
thrombosis. However, the molecular mechanisms that potentially link periodontitis with …