Ocular drug delivery: a comprehensive review
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
Nanotechnology-based ocular drug delivery systems: recent advances and future prospects
S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …
Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …
Self-assembling lecithin-based mixed polymeric micelles for nose to brain delivery of clozapine: In-vivo assessment of drug efficacy via radiobiological evaluation
FM Elsharkawy, MM Amin… - International Journal …, 2023 - Taylor & Francis
Purpose The research objective is to design intranasal brain targeted CLZ loaded lecithin
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …
A novel reverse micelle based cationic double nanoemulsion as a potential nanoplatform for enhancing the anitglucomal activity of betaxolol hydrochloride; …
Glaucoma is one of the most common causes of irreversible vision loss worldwide. The
hydrophilic nature of the anti-glaucoma drug Betaxolol hydrochloride (BH) limits its ocular …
hydrophilic nature of the anti-glaucoma drug Betaxolol hydrochloride (BH) limits its ocular …
Recent updates on ocular disease management with ophthalmic ointments
Ophthalmic diseases can result in permanent vision loss and blindness. Convenient topical
and systemic treatments are preferred to address these sight-threatening conditions …
and systemic treatments are preferred to address these sight-threatening conditions …
Cationized gelatin-sodium alginate polyelectrolyte nanoparticles encapsulating moxifloxacin as an eye drop to treat bacterial keratitis
A mucoadhesive polyelectrolyte complex (PEC) nanoparticles were developed for ocular
moxifloxacin (Mox) delivery in Bacterial Keratitis (BK). Moxifloxacin-loaded G/CG-Alg NPs …
moxifloxacin (Mox) delivery in Bacterial Keratitis (BK). Moxifloxacin-loaded G/CG-Alg NPs …
Pronounced capping effect of olaminosomes as nanostructured platforms in ocular candidiasis management
The aim of this study was to formulate and boost ocular targeting of Fenticonazole Nitrate
(FTN)-loaded olaminosomes in order to improve drug corneal permeation and candidiasis …
(FTN)-loaded olaminosomes in order to improve drug corneal permeation and candidiasis …
Review of nanoformulations for treating ocular fungal infections
AL Onugwu, SC Emencheta, RN Sabastine… - Journal of Drug Delivery …, 2024 - Elsevier
Ocular fungal infections affect more than one million people globally, of which fungal
keratitis and endophthalmitis are the most common. These infections are the primary cause …
keratitis and endophthalmitis are the most common. These infections are the primary cause …
Engineered lecithin-based proniosomes for enhanced trans-tympanic permeation: In vitro, microbiological, ex vivo and in vivo evaluation
Otitis media is an acute illness that specifically targets the middle ear. It affects around one-
third of the pediatric population in the US. This study aimed to develop lecithin-based …
third of the pediatric population in the US. This study aimed to develop lecithin-based …