Integrating plant molecular farming and materials research for next-generation vaccines

YH Chung, D Church, EC Koellhoffer, E Osota… - Nature Reviews …, 2022 - nature.com
Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …

Green synthesis of metallic nanoparticles via biological entities

M Shah, D Fawcett, S Sharma, SK Tripathy… - Materials, 2015 - mdpi.com
Nanotechnology is the creation, manipulation and use of materials at the nanometre size
scale (1 to 100 nm). At this size scale there are significant differences in many material …

Therapeutic recombinant protein production in plants: Challenges and opportunities

MJB Burnett, AC Burnett - Plants, People, Planet, 2020 - Wiley Online Library
Societal Impact Statement Therapeutic protein production in plants is an area of great
potential for increasing and improving the production of proteins for the treatment or …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

[HTML][HTML] Therapeutic vaccines for high-risk HPV-associated diseases

A Chabeda, RJR Yanez, R Lamprecht, AE Meyers… - Papillomavirus …, 2018 - Elsevier
Cancer is the second leading cause of death worldwide, and it is estimated that Human
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV …

Construction and characterization of virus-like particles: a review

A Zeltins - Molecular biotechnology, 2013 - Springer
Over the last three decades, virus-like particles (VLPs) have evolved to become a widely
accepted technology, especially in the field of vaccinology. In fact, some VLP-based …

Advances in plant molecular farming

OO Obembe, JO Popoola, S Leelavathi… - Biotechnology advances, 2011 - Elsevier
Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are
engineered to produce recombinant pharmaceutical and industrial proteins in large …

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

EP Rybicki - Wiley Interdisciplinary Reviews: Nanomedicine …, 2020 - Wiley Online Library
The use of plants for the production of virus‐like nanoparticles (VNPs) dates back to
separating natural empty capsids of plant viruses from whole virions nearly 70 years ago …

Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures

J Xu, X Ge, MC Dolan - Biotechnology advances, 2011 - Elsevier
“Molecular farming” in plants with significant advantages in cost and safety is touted as a
promising platform for the production of complex pharmaceutical proteins. While whole-plant …

Assessment of benefits and risk of genetically modified plants and products: current controversies and perspective

BK Ghimire, CY Yu, WR Kim, HS Moon, J Lee, SH Kim… - Sustainability, 2023 - mdpi.com
Genetic transformation has emerged as an important tool for the genetic improvement of
valuable plants by incorporating new genes with desirable traits. These strategies are useful …