Medication adherence: WHO cares?

MT Brown, JK Bussell - Mayo clinic proceedings, 2011 - Elsevier
The treatment of chronic illnesses commonly includes the long-term use of
pharmacotherapy. Although these medications are effective in combating disease, their full …

Impact of statin adherence on cardiovascular disease and mortality outcomes: a systematic review

MA De Vera, V Bhole, LC Burns… - British journal of clinical …, 2014 - Wiley Online Library
Aims While suboptimal adherence to statin medication has been quantified in real‐world
patient settings, a better understanding of its impact is needed, particularly with respect to …

Adjuvant endocrine therapy for women with hormone receptor–positive breast cancer: American Society of Clinical Oncology clinical practice guideline focused …

HJ Burstein, S Temin, H Anderson… - Journal of clinical …, 2014 - ascopubs.org
Purpose To update the ASCO clinical practice guideline on adjuvant endocrine therapy on
the basis of emerging data on the optimal duration of treatment, particularly adjuvant …

The effects of adherence and persistence on clinical outcomes in patients treated with statins: a systematic review

RJ Simpson Jr, P Mendys - Journal of clinical lipidology, 2010 - Elsevier
BACKGROUND: In clinical practice, medication adherence and persistence are important for
disease management and can significantly improve outcomes and enhance the quality of …

Non-adherence to statin therapy: a major challenge for preventive cardiology

TR Bates, VM Connaughton… - Expert opinion on …, 2009 - Taylor & Francis
Background: Hypercholesterolemia is a major risk factor for atherosclerosis and
cardiovascular disease, the leading cause of death worldwide. In the last twenty years …

Adherencia terapéutica en la enfermedad crónica: estado de la situación y perspectiva de futuro

P Conthe, EM Contreras, AA Pérez, BB García… - Revista clínica …, 2014 - Elsevier
Las enfermedades crónicas de larga duración poseen una elevada mortalidad y afectan por
igual a ambos sexos. La falta de adherencia a las recomendaciones terapéuticas continúa …

Statin treatment for primary prevention of vascular disease: whom to treat? Cost-effectiveness analysis

JP Greving, FLJ Visseren, GA De Wit, A Algra - Bmj, 2011 - bmj.com
Objective To assess the cost-effectiveness of low dose statins for primary prevention of
vascular disease, incorporating current prices, non-adherence (reduced clinical efficacy …

Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease

HF Hope, GM Binkley, S Fenton, GD Kitas… - PLoS …, 2019 - journals.plos.org
Introduction Previous research has shown that statin adherence for the primary prevention of
CVD is lower compared to secondary prevention populations. Therefore the aim of this …

Statin discontinuation in high-risk patients: a systematic review of the evidence

YH Gomez Sandoval, M V. Braganza… - Current …, 2011 - benthamdirect.com
Hypercholesterolemia is a major risk factor for cardiovascular disease (CVD), the leading
cause of death worldwide. Since the late 1980s, statins have emerged as effective lipid …

Long-term statin treatment in children with familial hypercholesterolemia: more insight into tolerability and adherence

MJAM Braamskamp, DM Kusters, HJ Avis, EMA Smets… - Pediatric Drugs, 2015 - Springer
Background Statins are currently the preferred pharmacological therapy in individuals with
familial hypercholesterolemia (FH) with the aim to prevent premature atherosclerosis. In …