[HTML][HTML] Chemotherapy-induced neutropenia and emerging agents for prevention and treatment: a review
DW Blayney, L Schwartzberg - Cancer treatment reviews, 2022 - Elsevier
Highlights•Chemotherapy-induced neutropenia can lead to poor clinical outcomes.•CIN can
lead to infections, hospitalizations, mortality, and lower chemotherapy dose intensity.•G-CSF …
lead to infections, hospitalizations, mortality, and lower chemotherapy dose intensity.•G-CSF …
Engineered therapeutic proteins for sustained-release drug delivery systems
TTK Nguyen, KY Pham, S Yook - Acta Biomaterialia, 2023 - Elsevier
Proteins play a vital role in diverse biological processes in the human body, and protein
therapeutics have been applied to treat different diseases such as cancers, genetic …
therapeutics have been applied to treat different diseases such as cancers, genetic …
Expression, Purification, and Biological Evaluation of XTEN-GCSF in a Neutropenic Rat Model
FY Nikravesh, P Gholami, E Bayat, Y Talebkhan… - Applied Biochemistry …, 2024 - Springer
Granulocyte colony-stimulating factor (GCSF) stimulates the proliferation of neutrophils but it
has low serum half-life. Therefore, the present study was done to investigate the effect of …
has low serum half-life. Therefore, the present study was done to investigate the effect of …
Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy
X Liu, K Vanvarenberg, KGW Kouassi, S Mahri… - International journal of …, 2022 - Elsevier
Abstract Alpha-1 antitrypsin (AAT) is an endogenous inhibitor of serine proteases which, in
physiological conditions, neutralizes the excess of neutrophil elastase and other serine …
physiological conditions, neutralizes the excess of neutrophil elastase and other serine …
Recombinant expression, purification and PEGylation of DNA Ligases
LK Zuma, NL Gasa, X Mazibuko… - Protein and Peptide …, 2022 - ingentaconnect.com
Background: Reagent proteins such as DNA ligases play a central role in the global
reagents market. DNA ligases are commonly used and are vital in academic and science …
reagents market. DNA ligases are commonly used and are vital in academic and science …
[HTML][HTML] Optimizing Granulocyte Colony-Stimulating Factor Transcript for Enhanced Expression in Escherichia coli
S Datta - Frontiers in bioengineering and biotechnology, 2021 - frontiersin.org
The human granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor
used to prevent and treat neutropenia. G-CSF stimulates the bone marrow to produce …
used to prevent and treat neutropenia. G-CSF stimulates the bone marrow to produce …