Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects

C Backes, E Meese, A Keller - Molecular diagnosis & therapy, 2016 - Springer
Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …

Profiles of radioresistance mechanisms in prostate cancer

L Chaiswing, HL Weiss, RD Jayswal… - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Radiation therapy (RT) is commonly used for the treatment of localized prostate cancer
(PCa). However, cancer cells often develop resistance to radiation through unknown …

Exosomal microRNAs-mediated intercellular communication and exosome-based cancer treatment

ZY Shi, XX Yang, CY Malichewe, YS Li… - International journal of …, 2020 - Elsevier
Exosomes are extracellular vesicles with a diameter of about 30 to 100 nm, which play a
crucial role in intercellular communication. Compared with normal cells, the release rate of …

Stroma‐derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer

AP Shephard, P Giles, M Mbengue… - Journal of …, 2021 - Wiley Online Library
Histological assessment of prostate cancer is the key diagnostic test and can predict disease
outcome. This is however an invasive procedure that carries associated risks, hence non …

Searching for the novel specific predictors of prostate cancer in urine: the analysis of 84 miRNA expression

EA Lekchnov, EV Amelina, OE Bryzgunova… - International journal of …, 2018 - mdpi.com
The aim of this study was to investigate miRNA profiles of clarified urine supernatant and
combined urine vesicle fractions of healthy donors and patients with benign prostatic …

Unveiling potential: urinary exosomal mRNAs as non-invasive biomarkers for early prostate cancer diagnosis

J Yu, C Yu, K Jiang, G Yang, S Yang, S Tan, T Li… - BMC urology, 2024 - Springer
Background This study investigated the use of urinary exosomal mRNA as a potential
biomarker for the early detection of prostate cancer (PCa). Methods Next-generation …

[HTML][HTML] Serum calcium level at diagnosis can predict Lethal prostate Cancer Relapse

Z Fekete, P Ignat, H Jakab, N Todor, IP László… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: The most important prognostic factors in curatively treated prostate
cancer are T and N stage, histology, grade group and initial PSA. A recent study found that …

Locus-specific methylation of GSTP1, RNF219, and KIAA1539 genes with single molecule resolution in cell-free DNA from healthy donors and prostate tumor patients …

O Bryzgunova, A Bondar, P Ruzankin, P Laktionov… - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer (PCa) is the second most commonly diagnosed cancer in
men, which is constantly accompanied by benign prostate hyperplasia (BPH). To reach a …

Locus-Specific Bisulfate NGS Sequencing of GSTP1, RNF219, and KIAA1539 Genes in the Total Pool of Cell-Free and Cell-Surface-Bound DNA in Prostate Cancer: A …

O Bryzgunova, A Bondar, P Ruzankin, A Tarasenko… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) is a global problem in the modern world. PCa has
an almost 100% five-year relative survival rate at localized and regional stages and 31% at …

Development and validation of a urinary microRNA biomarker panel as a tool for early detection of prostate cancer in a Chinese population

N Zhang, J Wang, S Zhang, H Wu, Z Li, M Hu - Biomarkers, 2023 - Taylor & Francis
Abstract Introduction Urinary microRNAs (miRNAs) may serve as promising biomarkers for
non-invasive early detection of prostate cancer (PCa). We aimed to identify multi-miRNA …