Versatile spider venom peptides and their medical and agricultural applications

NJ Saez, V Herzig - Toxicon, 2019 - Elsevier
Spiders have been evolving complex and diverse repertoires of peptides in their venoms
with vast pharmacological activities for more than 300 million years. Spiders use their …

Recombinant anti-HIV MAP30, a ribosome inactivating protein: against plant virus and bacteriophage

N Amirzadeh, A Moghadam, A Niazi, A Afsharifar - Scientific Reports, 2023 - nature.com
The ribosome inactivating proteins (RIPs) efficiently decrease the microbial infections in
plants. Momordica charantia MAP30 is a type I RIP that has not been investigated against …

Expression of a Recombinant Anti-HIV and Anti-Tumor Protein, MAP30, in Nicotiana tobacum Hairy Roots: A pH-Stable and Thermophilic Antimicrobial Protein

A Moghadam, A Niazi, A Afsharifar, SM Taghavi - PloS one, 2016 - journals.plos.org
In contrast to conventional antibiotics, which microorganisms can readily evade, it is nearly
impossible for a microbial strain that is sensitive to antimicrobial proteins to convert to a …

First generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin

LFRN de Moraes, PS Silva, TCPL Pereira… - Frontiers in …, 2022 - frontiersin.org
The need for discovering new compounds that can act selectively on pathogens is becoming
increasingly evident, given the number of deaths worldwide due to bacterial infections or …

[图书][B] Natural substances for cancer prevention

JP Xu - 2018 - taylorfrancis.com
Natural Substances for Cancer Prevention explores in detail how numerous investigations in
chemical biology and molecular biology have established strong scientific evidence …

A preliminary study in search of potential peptide candidates for a combinational therapy with cancer chemotherapy drug

HA Rothan, J Ambikabothy, TS Ramasamy… - International Journal of …, 2019 - Springer
Cancer which caused by the growth and spreading of abnormal cells in an uncontrolled
manner remains a major cause of death affecting millions of people. The current cancer …

Momordica charantia L., uma planta medicinal e seu potencial antitumoral: uma revisão sistemática

TD da Silva, PGVD de Souza - Brazilian Journal of …, 2020 - ojs.brazilianjournals.com.br
A Momordica charantia, popularmente conhecida como melão de São Caetano, é uma
planta da família das Cucurbitáceas e sua principal característica é seu sabor amargo. O …

Evaluation of neutralizing antibodies produced by papaya mosaic virus nanoparticles fused to the E2EP3 peptide epitope of Chikungunya envelope.

TC Teoh, SJ Al-Harbi, R Yusof, HA Rothan - Tropical Biomedicine, 2021 - europepmc.org
Chikungunya virus (CHIKV) infection is the cause of acute symptoms and chronic
symmetrical polyarthritis associated with long-term morbidity and mortality. Currently, there …

Venom Peptides and Toxins-A Prospective Spearhead in Cancer Treatment

J PC Wong, B Li, H F. Kwok - Combinatorial Chemistry & High …, 2017 - benthamdirect.com
Background & Aim: Cancer is a condition of genetically or environmentally mutated,
uncontrollable cell growth that directly affects human morbidity and mortality. Many …

[PDF][PDF] Synthetic peptide optimization improves the inhibition of dengue NS2B-NS3 protease and dengue replication in vitro

AY Abdulrahman, HA Rothan, AS Khazali… - Acta …, 2019 - researchgate.net
Dengue virus (DENV) infection is one of the most widely-spread flavivirus infections with no
effective antiviral drugs available. Peptide inhibitors have been considered as one of the …