Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Periodontal disease is a major public health issue, and various periodontal therapies have
been performed to regenerate periodontal tissues. The periodontium is a complex structure …

Diabetic peripheral neuropathy (DPN) is caused by hyperglycemia, which induces oxidative
stress and inflammatory responses that damage nerve tissue. Excessive generation of …

Palmitoylethanolamide (PEA, N-hexadecanoylethanolamide) is an endogenous compound
belonging to the family of N-acylethanolamines. PEA has anti-inflammatory and analgesic …

TBI (traumatic brain injury) is a major cause of death among youth in industrialized societies.
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …

Ageing represents the single biggest risk factor for development of neurodegenerative
disease. Despite being such long-lived cells, microglia have been relatively understudied for …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and
devastating clinical disorders with high mortality and no specific therapy …

Neuropathic pain results from lesions or diseases of the somatosensory nervous system and
it remains largely difficult to treat. Peripheral neuropathic pain originates from injury to the …

Fibromyalgia is a chronic condition characterized by persistent widespread pain that
significantly reduces quality of life in patients. The purinergic P2X7 receptor (P2X7R) seems …

Background: Chronic pulmonary diseases are characterized by airway remodeling due to
complex multicellular responses and the production of free oxygen radicals. They lead to a …