Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically
important complication in adult patients undergoing open heart surgery, and is associated …

Acute kidney injury (AKI) is a common complication in cardiac surgery patients, with a
reported incidence of 20 to 30%. The development of AKI is associated with worse short-and …

Discoveries have emerged highlighting the complex nature of the interorgan cross-talk
between the kidney and the lung. Vascular rigidity, neurohormonal activation, tissue …

Intravascular haemolysis is a fundamental feature of chronic hereditary and acquired
haemolytic anaemias, including those associated with haemoglobinopathies, complement …

Rationale: No medical intervention has been identified that decreases acute kidney injury
and improves renal outcome at 1 year after cardiac surgery. Objectives: To determine …

The complex nature of single organ failure potentially leading to multiple organ dysfunction
syndrome (MODS) in critically ill patients necessitates integrated supportive therapy. Rather …

Acute kidney injury (AKI) is a common and serious complication of cardiac surgery and is
associated with increased mortality and morbidity, accompanied by a substantial economic …

Intravascular hemolysis can result in hemoglobinuria with acute kidney injury. In this study
we systematically explored two in vivo animal models and a related cell culture system to …

The aim of the study was to explore the prevalence and risk factors for technical-induced
hemolysis in adults supported with veno-venous extracorporeal membrane oxygenation …

Hemolysis (ie, red blood cell lysis) can increase circulatory levels of cell-free hemoglobin
(Hb) and its degradation by-products, namely heme (h) and iron (Fe). Under homeostasis …