[HTML][HTML] Emerging methods and applications of ultra-high field MR spectroscopic imaging in the human brain

G Hangel, E Niess, P Lazen, P Bednarik, W Bogner… - Analytical …, 2022 - Elsevier
Abstract Magnetic Resonance Spectroscopic Imaging (MRSI) of the brain enables insights
into the metabolic changes and fluxes in diseases such as tumors, multiple sclerosis …

Glioblastoma multiforme prognosis: MRI missing modality generation, segmentation and radiogenomic survival prediction

M Islam, N Wijethilake, H Ren - Computerized Medical Imaging and …, 2021 - Elsevier
The accurate prognosis of glioblastoma multiforme (GBM) plays an essential role in
planning correlated surgeries and treatments. The conventional models of survival …

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay

L Rumping, F Tessadori, PJW Pouwels… - Human molecular …, 2019 - academic.oup.com
Loss-of-function mutations in glutaminase (GLS), the enzyme converting glutamine into
glutamate, and the counteracting enzyme glutamine synthetase (GS) cause disturbed …

A multi‐inversion multi‐echo spin and gradient echo echo planar imaging sequence with low image distortion for rapid quantitative parameter mapping and synthetic …

MK Manhard, J Stockmann, C Liao… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose Brain imaging exams typically take 10‐20 min and involve multiple sequential
acquisitions. A low‐distortion whole‐brain echo planar imaging (EPI)‐based approach was …

Lipid‐suppressed and tissue‐fraction corrected metabolic distributions in human central brain structures using 2D 1H magnetic resonance spectroscopic imaging at 7 …

AA Bhogal, TAA Broeders, L Morsinkhof… - Brain and …, 2020 - Wiley Online Library
Introduction Magnetic resonance spectroscopic imaging (MRSI) has the potential to add a
layer of understanding of the neurobiological mechanisms underlying brain diseases …

An Amyloid-β Targeting Chemical Exchange Saturation Transfer Probe for In Vivo Detection of Alzheimer's Disease

R Wang, C Wang, Z Dai, Y Chen, Z Shen… - ACS Chemical …, 2019 - ACS Publications
A reliable and reproducible detection of Aβ deposits would be beneficial for the early
diagnosis of Alzheimer's disease (AD). In the present study, the feasibility of applying …

Proton metabolic mapping of the brain at 7 T using a two‐dimensional free induction decay–echo‐planar spectroscopic imaging readout with lipid suppression

KM Nam, AD Hendriks, VO Boer… - NMR in …, 2022 - Wiley Online Library
The increased signal‐to‐noise ratio (SNR) and chemical shift dispersion at high magnetic
fields (≥ 7 T) have enabled neuro‐metabolic imaging at high spatial resolutions. To avoid …

Enhancing Whole-Brain Magnetic Field Homogeneity for 3D-Magnetic Resonance Spectroscopic Imaging with a Novel Unified Coil: A Preliminary Study

AV Malagi, X Li, N Zhang, Y Liu, Y Huang, FM Serry… - Cancers, 2024 - mdpi.com
Simple Summary Magnetic resonance spectroscopic imaging (MRSI) plays an increasingly
important role in the non-invasive diagnosis and treatment planning of gliomas. This study …

Fast online spectral-spatial pulse design for subject-specific fat saturation in cervical spine and foot imaging at 1.5 T

CK Eisen, P Liebig, J Herrler, D Ritter, S Lévy… - … Resonance Materials in …, 2024 - Springer
Objective To compensate subject-specific field inhomogeneities and enhance fat pre-
saturation with a fast online individual spectral-spatial (SPSP) single-channel pulse design …

Glutamate levels across deep brain structures in patients with a psychotic disorder and its relation to cognitive functioning

TAA Broeders, AA Bhogal… - Journal of …, 2022 - journals.sagepub.com
Background: Patients with psychotic disorders often show prominent cognitive impairment.
Glutamate seems to play a prominent role, but its role in deep gray matter (DGM) regions is …