Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives

MF Dias, K Joo, JA Kemp, SL Fialho… - Progress in retinal and …, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …

[HTML][HTML] Mechanisms of age-related macular degeneration

J Ambati, BJ Fowler - Neuron, 2012 - cell.com
Age-related macular degeneration (AMD), a progressive condition that is untreatable in up
to 90% of patients, is a leading cause of blindness in the elderly worldwide. The two forms of …

[HTML][HTML] Human eye-inspired soft optoelectronic device using high-density MoS2-graphene curved image sensor array

C Choi, MK Choi, S Liu, M Kim, OK Park, C Im… - Nature …, 2017 - nature.com
Soft bioelectronic devices provide new opportunities for next-generation implantable
devices owing to their soft mechanical nature that leads to minimal tissue damages and …

The Argus® II retinal prosthesis system

YHL Luo, L Da Cruz - Progress in retinal and eye research, 2016 - Elsevier
Abstract The Argus® II Retinal Prosthesis System (Second Sight Medical Products) is the
first prosthetic vision device to obtain regulatory approval in both Europe and the USA. As …

[HTML][HTML] Subretinal visual implant alpha IMS–clinical trial interim report

K Stingl, KU Bartz-Schmidt, D Besch, CK Chee… - Vision research, 2015 - Elsevier
A subretinal visual implant (Alpha IMS, Retina Implant AG, Reutlingen, Germany) was
implanted in 29 blind participants with outer retinal degeneration in an international …

An insight into assistive technology for the visually impaired and blind people: state-of-the-art and future trends

A Bhowmick, SM Hazarika - Journal on Multimodal User Interfaces, 2017 - Springer
Assistive technology for the visually impaired and blind people is a research field that is
gaining increasing prominence owing to an explosion of new interest in it from disparate …

Bioinspired artificial eyes: optic components, digital cameras, and visual prostheses

GJ Lee, C Choi, DH Kim… - Advanced Functional …, 2018 - Wiley Online Library
The diverse vision systems found in nature can provide interesting design inspiration for
imaging devices, ranging from optical subcomponents to digital cameras and visual …

An update on retinal prostheses

LN Ayton, N Barnes, G Dagnelie, T Fujikado… - Clinical …, 2020 - Elsevier
Retinal prostheses are designed to restore a basic sense of sight to people with profound
vision loss. They require a relatively intact posterior visual pathway (optic nerve, lateral …

Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration

H Shirai, M Mandai, K Matsushita… - Proceedings of the …, 2016 - National Acad Sciences
Retinal transplantation therapy for retinitis pigmentosa is increasingly of interest due to
accumulating evidence of transplantation efficacy from animal studies and development of …

Photovoltaic restoration of sight with high visual acuity

H Lorach, G Goetz, R Smith, X Lei, Y Mandel… - Nature medicine, 2015 - nature.com
Patients with retinal degeneration lose sight due to the gradual demise of photoreceptors.
Electrical stimulation of surviving retinal neurons provides an alternative route for the …