A prospective view of animal and human Fasciolosis

K Cwiklinski, SM O'neill, S Donnelly… - Parasite …, 2016 - Wiley Online Library
Fasciolosis, a food‐borne trematodiasis, results following infection with the parasites,
Fasciola hepatica and Fasciola gigantica. These trematodes greatly affect the global …

A review of our current understanding of parasite survival in silage and stored forages, with a focus on Fasciola hepatica metacercariae

BC John, DR Davies, DJL Williams… - Grass and Forage …, 2019 - Wiley Online Library
Fasciola hepatica, the parasitic liver fluke, is a re‐emerging zoonotic infection and an
important cause of morbidity and mortality in ruminant livestock worldwide. A significant …

A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance

NJ Beesley, K Cwiklinski, K Allen, RC Hoyle… - PLoS …, 2023 - journals.plos.org
Fasciola hepatica infection is responsible for substantial economic losses in livestock
worldwide and poses a threat to human health in endemic areas. The mainstay of control in …

[HTML][HTML] Fasciola hepatica demonstrates high levels of genetic diversity, a lack of population structure and high gene flow: possible implications for drug resistance

NJ Beesley, DJL Williams, S Paterson… - International journal for …, 2017 - Elsevier
Fasciola hepatica, the liver fluke, is a trematode parasite of considerable economic
importance to the livestock industry and is a re-emerging zoonosis that poses a risk to …

Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts

XX Zhang, K Cwiklinski, RS Hu, WB Zheng, ZA Sheng… - BMC genomics, 2019 - Springer
Background The tropical liver fluke, Fasciola gigantica causes fasciolosis, an important
disease of humans and livestock. We characterized dynamic transcriptional changes …

Resequencing helminth genomes for population and genetic studies

J Wit, JS Gilleard - Trends in parasitology, 2017 - cell.com
Next-generation sequencing has become increasingly accessible and economical, making
genome-wide studies routine for many species, including humans, model organisms, and …

Clonal amplification of Fasciola hepatica in Galba truncatula: within and between isolate variation of triclabendazole-susceptible and-resistant clones

JE Hodgkinson, K Cwiklinski, N Beesley, C Hartley… - Parasites & vectors, 2018 - Springer
Background Fasciola hepatica is of worldwide significance, impacting on the health, welfare
and productivity of livestock and regarded by WHO as a re-emerging zoonosis …

[HTML][HTML] Evidence of population structuring following population genetic analyses of Fasciola hepatica from Argentina

NJ Beesley, E Attree, S Vázquez-Prieto, R Vilas… - International journal for …, 2021 - Elsevier
Fasciola hepatica, the liver fluke, is a trematode parasite that causes disease of economic
importance in livestock. As a zoonosis this parasite also poses a risk to human health in …

Genetic diversity and relationships of the liver fluke Fasciola hepatica (Trematoda) with native and introduced definitive and intermediate hosts

AA Vázquez, E Sabourin, P Alda… - Transboundary and …, 2021 - Wiley Online Library
Fasciolosis is a worldwide spread parasitosis mainly caused by the trematode Fasciola
hepatica. This disease is particularly important for public health in tropical regions, but it can …

Design and expression of polytopic construct of cathepsin-L1, SAP-2 and FhTP16. 5 proteins of Fasciola hepatica

S Aghamolaei, B Kazemi, M Bandehpour… - Journal of …, 2020 - cambridge.org
The enzyme-linked immunosorbent assay (ELISA) technique can play an important role in
the early detection of fascioliasis. However, they have some diagnostic limitations, including …