There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Simple Summary Boron neutron capture therapy (BNCT) is a tumor-selective particle
radiotherapy. It combines preferential boron accumulation in tumors and neutron irradiation …

In the present work, a convenient and straightforward approach to the preparation of
borylated amidines based on the closo-dodecaborate anion [B12H11NCCH3NHR]−, R= H …

About 25 years ago, Bogdanovic and Schwickardi (B. Bogdanovic, M. Schwickardi: J. Alloys
Compd. 1–9, 253 (1997) discovered the catalyzed release of hydrogen from NaAlH4. This …

This proceeding article compiles current research on the development of boron delivery
drugs for boron neutron capture therapy that was presented and discussed at the National …

Visible‐light‐induced photoreaction of carboranes is an effective approach to prepare
carborane‐containing compounds. While several methods involving boron‐centered …

Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of
benzene. It features special physical and chemical properties, and thus has the potential to …

Traditionally, drugs were obtained by extraction from medicinal plants, but more recently
also by organic synthesis. Today, medicinal chemistry continues to focus on organic …

Glioblastoma (GBM), as the most central nervous system (CNS) intractable disease, has
spoiled millions of lives due to its high mortality. Even though several efforts have been …