Anti-viral triterpenes: a review

P Darshani, S Sen Sarma, AK Srivastava… - Phytochemistry …, 2022 - Springer
Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of
Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic …

Congenital Zika syndrome: genetic avenues for diagnosis and therapy, possible management and long-term outcomes

G Gullo, M Scaglione, G Cucinella, A Riva… - Journal of Clinical …, 2022 - mdpi.com
Zika virus (ZIKV) was discovered in Uganda in 1947 and was originally isolated only in
Africa and Asia. After a spike of microcephaly cases in Brazil, research has closely focused …

The citrus flavonoid naringenin impairs the in vitro infection of human cells by Zika virus

AHD Cataneo, D Kuczera, AC Koishi, C Zanluca… - Scientific Reports, 2019 - nature.com
The Zika virus (ZIKV) is an arthropod-borne virus that belongs to the Flaviviridae family. The
ZIKV infection is usually asymptomatic or is associated with mild clinical manifestations; …

Development of a quantitative NS1 antigen enzyme-linked immunosorbent assay (ELISA) for Zika virus detection using a novel virus-specific mAb

SV Morales, GM Coelho, T Ricciardi-Jorge, GG Dorl… - Scientific Reports, 2024 - nature.com
Viruses from the Flaviviridae family, such as Dengue virus (DENV), Yellow fever virus (YFV),
and Zika virus (ZIKV) are notorious global public health problems. ZIKV emergence in …

An overview of Zika virus genotypes and their infectivity

LC Bernardo-Menezes, A Agrelli… - Revista da Sociedade …, 2022 - SciELO Brasil
Zika virus (ZIKV) is an enveloped, single-stranded RNA arbovirus belonging to the genus
Flavivirus. It was first isolated from a sentinel monkey in Uganda in 1947. More recently …

Picking up a fight: fine tuning mitochondrial innate immune defenses against RNA viruses

S Dutta, N Das, P Mukherjee - Frontiers in microbiology, 2020 - frontiersin.org
As the world faces the challenge of the COVID-19 pandemic, it has become an urgent need
of the hour to understand how our immune system sense and respond to RNA viruses that …

Antiviral activity of ouabain against a Brazilian Zika virus strain

DCM Carvalho, PG da Silva, WM Dantas… - Scientific Reports, 2022 - nature.com
Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently,
no specific vaccines or antivirals are available to treat the ZIKV infection. Ouabain, a …

Comparative analysis of in vitro models to study antibody-dependent enhancement of Zika virus infection

T Langerak, N Mumtaz, M Koopmans, S Schoenmakers… - Viruses, 2022 - mdpi.com
During the 2015–2016 outbreak of Zika virus (ZIKV) in the Americas, a previously unknown
severe complication of ZIKV infection during pregnancy resulting in birth defects was …

Zika virus serological diagnosis: commercial tests and monoclonal antibodies as tools

IBB Silva, AS Silva, MS Cunha, AD Cabral… - Journal of Venomous …, 2020 - SciELO Brasil
Zika virus (ZIKV), an emerging arthropod-borne virus (arbovirus) of the Flaviviridae family, is
a current issue worldwide, particularly because of the congenital and neurological …

DNA-PKcs restricts Zika virus spreading and is required for effective antiviral response

DO Patricio, GBM Dias, LW Granella, B Trigg… - Frontiers in …, 2022 - frontiersin.org
Zika virus (ZIKV) is a single-strand RNA mosquito-borne flavivirus with significant public
health impact. ZIKV infection induces double-strand DNA breaks (DSBs) in human neural …