LOX-1 and ROS, inseparable factors in the process of endothelial damage

V Lubrano, S Balzan - Free Radical Research, 2014 - Taylor & Francis
Lectin-like oxidized low-density lipoprotein (LOX-1) has been identified in endothelial cells
as the main receptor of oxidized low-density lipoprotein (OxLDL). LOX-1 is upregulated in …

Therapeutic strategies for oxidative stress‐related cardiovascular diseases: removal of Excess Reactive oxygen species in adult stem cells

H Kim, J Yun, SM Kwon - Oxidative Medicine and Cellular …, 2016 - Wiley Online Library
Accumulating evidence indicates that acute and chronic uncontrolled overproduction of
oxidative stress‐related factors including reactive oxygen species (ROS) causes …

Anti-inflammatory and antioxidant effect of fermented whole wheat on TNFα-stimulated HT-29 and NF-κB signaling pathway activation

M Gabriele, L Pucci, J Árvay, V Longo - Journal of Functional Foods, 2018 - Elsevier
The present study compared the phenolic profile, the in vitro and ex vivo antioxidant activity,
as well as the anti-inflammatory effect of fermented (LG) and unfermented (FG) whole wheat …

A fermented whole grain prevents lipopolysaccharides‐induced dysfunction in human endothelial progenitor cells

L Giusti, M Gabriele, G Penno… - Oxidative Medicine …, 2017 - Wiley Online Library
Endogenous and exogenous signals derived by the gut microbiota such as
lipopolysaccharides (LPS) orchestrate inflammatory responses contributing to development …

Diet bioactive compounds: implications for oxidative stress and inflammation in the vascular system

M Gabriele, L Pucci - Endocrine, Metabolic & Immune Disorders …, 2017 - ingentaconnect.com
Background and Objective: Increasing evidence has demonstrated that dietary products and
their active components are independently or jointly responsible for the apparent reduction …

Fermented wheat powder induces the antioxidant and detoxifying system in primary rat hepatocytes

M La Marca, P Beffy, A Pugliese, V Longo - PLoS One, 2013 - journals.plos.org
Many plants exhibit antioxidant properties which may be useful in the prevention of oxidative
stress reactions, such as those mediated by the formation of free radical species in different …

Study on a fermented whole wheat: Phenolic content, activity on PTP1B enzyme and in vitro prebiotic properties

D Balli, M Bellumori, P Paoli, G Pieraccini, M Di Paola… - Molecules, 2019 - mdpi.com
Fermented cereals, staple foods in Asia and Africa, are recently receiving a growing interest
in Western countries. The object of this work is the characterization of a fermented wheat …

Grain and bean lysates improve function of endothelial progenitor cells from human peripheral blood: involvement of the endogenous antioxidant defenses

D Lucchesi, R Russo, M Gabriele, V Longo… - PLoS …, 2014 - journals.plos.org
Increased oxidative stress contributes to the functional impairment of endothelial progenitor
cells (EPCs), the pivotal players in the servicing of the endothelial cell lining. Several …

A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL

M Gabriele, L Pucci, M La Marca, D Lucchesi… - Cellular & Molecular …, 2016 - Springer
This study focused on an extract from fermented flour from the Lady Joy variety of the
common bean Phaseolus vulgaris. The extract, Lady Joy lysate (Lys LJ), is enriched in …

The effects of fermented wheat powder (Lisosan G) on the blood lipids and oxidative status of healthy rabbits

L Pozzo, F Vizzarri, M Ciardi, M Nardoia… - Food and Chemical …, 2015 - Elsevier
A number of studies have shown that whole grain products have strong antioxidant effects.
Lisosan G, a powder produced from the fermentation of Triticum aestivum, has shown …