Current perspectives and difficulties in the design of acaricides and repellents from plant-derived compounds for tick control

N Malak, S Niaz, E Miranda-Miranda… - … and Applied Acarology, 2024 - Springer
Ticks and tick-borne diseases have gained increasing attention in recent years due to their
impact on public health and significant losses in livestock production. The use of synthetic …

Molecular targets for the development of new acaricides against Rhipicephalus microplus: a review

APM Cerqueira, M da Cunha Santos… - Parasitology, 2022 - cambridge.org
The cattle tick Rhipicephalus microplus is an ectoparasite with high economic importance to
bovine culture, mainly in tropical and subtropical regions. The resistance of the tick from the …

Explicit molecular dynamics simulation studies to discover novel natural compound analogues as Mycobacterium tuberculosis inhibitors

S Rampogu, B Shaik, JH Kim, TS Jung, MW Ha… - Heliyon, 2023 - cell.com
Tuberculosis (TB) in one of the dreadful diseases present globally. This is caused by
Mycobacterium tuberculosis. Mycobacterium tuberculosis dethiobiotin synthetase (MtDTBS) …

Identification of a novel protein Hq023 of the hard tick Haemaphysalis qinghaiensis and preliminary evaluation of its analgesic effect in mice model

T Xian, M Cao, K Chen, W Zhao, Y Liu, W Yao… - Parasitology …, 2024 - Elsevier
Tick saliva contains a range of critical biological molecules which could inhibit host defenses
and guarantee their food supply. Hq023, a novel cDNA sequence, was cloned from a cDNA …

[HTML][HTML] Development and Evaluation of the Acaricidal Activity of Xantan Gum-Based Hydrogel and Polymeric Nanoparticles Containing Achyrocline satureioides …

RR Fantatto, AR Gomes, JVC Constantini, CF Rodero… - Gels, 2024 - mdpi.com
The Rhipicephalus microplus tick causes enormous economic losses in livestock farming
around the world. Despite several promising studies carried out with plant extracts such as …

Genome-wide identification and expression profiling of duplicated flavonoid 3'-hydroxylase gene family in Carthamus tinctorius L.

NQV Hoang, JIE Kong, N Ahmad… - Notulae Botanicae …, 2021 - notulaebotanicae.ro
Abstract Flavonoid 3'-hydroxylase (F3" H) enzyme is essential in determining the flavonoids
B-ring hydroxylation pattern. It is mainly implicated in the biosynthetic pathway of cyaniding …

Anti-biofilm effect of ferulic acid against Enterobacter hormaechei and Klebsiella pneumoniae: in vitro and in silico investigation

P Vaikkathillam, M Mini, A Mohan, D Jayakumar… - Biofouling, 2024 - Taylor & Francis
Enterobacter hormaechei and Klebsiella pneumoniae, key members of the ESKAPE group
of hospital-acquired pathogens, are driving forces behind numerous infections due to their …

Antibiofilm potential of gallic acid against Klebsiella pneumoniae and Enterobacter hormaechei: in-vitro and in-silico analysis

PP Rajan, P Kumar, M Mini, D Jayakumar… - Biofouling, 2023 - Taylor & Francis
Biofilm refers to a community of microorganisms that adhere to a substrate and play a crucial
role in microbial pathogenesis and developing infections associated with medical devices …

Mining gene expression data for rational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus

C Maritz-Olivier, M Ferreira, NA Olivier… - … and Applied Acarology, 2023 - Springer
Control of complex parasites via vaccination remains challenging, with the current
combination of vaccines and small drugs remaining the choice for an integrated control …

Identification of potent inhibitors targeting Tribolium castaneum GSTe2 via structure-based screening and molecular dynamics simulation

KC Kim, W Zhang, P Chen, C Li, B Li - Journal of Biomolecular …, 2024 - Taylor & Francis
Red flour beetle, Tribolium castaneum, has a major negative impact during storage of
agricultural products and reveals the negative impacts on human health. Insect-specific …