Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Commercially available ocular drug delivery systems are effective but less efficacious to
manage diseases/disorders of the anterior segment of the eye. Recent advances in …

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were designed as
exceptionally safe colloidal carriers for the delivery of poorly soluble drugs. SLN/NLC have …

In the recent decades, various controlled delivery systems have been introduced with the
aim to improve solubility, stability and bioavailability of poorly absorbed drugs. Among all …

Statins, widely prescribed for cardiovascular diseases, are also being eyed for management
of age-related macular degeneration (AMD). Poor bioavailability and blood-aqueous barrier …

Introduction: Although eye drops are widely used as drug delivery systems for the anterior
segment of the eye, they are also associated with poor drug bioavailability due to transient …

The effective delivery of drugs to the eye remains a challenge. The eye has a myriad of
defense systems and physiological barriers that leaves ocular drug delivery systems with …

The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid lipid
nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure …

Curcumin loaded solid lipid nanoparticles (CSLNs) and probiotic (Lactobacillus plantarum
UBLP-40; L. plantarum) were currently co-incorporated into a wound dressing. The …

Ketoconazole (KET), a synthetic imidazole broad-spectrum antifungal agent, is
characterized by its poor aqueous solubility and high molecular weight, which might hamper …