The mitophagy pathway and its implications in human diseases

S Wang, H Long, L Hou, B Feng, Z Ma, Y Wu… - Signal transduction and …, 2023 - nature.com
Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

Mechanisms of selective autophagy

T Lamark, T Johansen - Annual review of cell and …, 2021 - annualreviews.org
Selective autophagy is the lysosomal degradation of specific intracellular components
sequestered into autophagosomes, late endosomes, or lysosomes through the activity of …

[HTML][HTML] Selective autophagy: ATG8 family proteins, LIR motifs and cargo receptors

T Johansen, T Lamark - Journal of molecular biology, 2020 - Elsevier
Selective autophagy relies on soluble or membrane-bound cargo receptors that recognize
cargo and bring about autophagosome formation at the cargo. The cargo-bound receptors …

A diversity of selective autophagy receptors determines the specificity of the autophagy pathway

V Kirkin, VV Rogov - Molecular cell, 2019 - cell.com
The clearance of surplus, broken, or dangerous components is key for maintaining cellular
homeostasis. The failure to remove protein aggregates, damaged organelles, or intracellular …

Autophagy: the master of bulk and selective recycling

RS Marshall, RD Vierstra - Annual review of plant biology, 2018 - annualreviews.org
Plants have evolved sophisticated mechanisms to recycle intracellular constituents, which
are essential for developmental and metabolic transitions; for efficient nutrient reuse; and for …

Cleaning house: selective autophagy of organelles

AL Anding, EH Baehrecke - Developmental cell, 2017 - cell.com
The selective clearance of organelles by autophagy is critical for the regulation of cellular
homeostasis in organisms from yeast to humans. Removal of damaged organelles clears …

A guide to the regulation of selective autophagy receptors

A Gubas, I Dikic - The FEBS journal, 2022 - Wiley Online Library
Autophagy is a highly conserved catabolic process cells use to maintain their homeostasis
by degrading misfolded, damaged and excessive proteins, nonfunctional organelles, foreign …

Autophagy promotes jasmonate-mediated defense against nematodes

J Zou, X Chen, C Liu, M Guo, MK Kanwar, Z Qi… - Nature …, 2023 - nature.com
Autophagy, as an intracellular degradation system, plays a critical role in plant immunity.
However, the involvement of autophagy in the plant immune system and its function in plant …

NBR1: The archetypal selective autophagy receptor

NL Rasmussen, A Kournoutis, T Lamark… - Journal of Cell …, 2022 - rupress.org
NBR1 was discovered as an autophagy receptor not long after the first described vertebrate
autophagy receptor p62/SQSTM1. Since then, p62 has currently been mentioned in> 10,000 …

A tripartite rheostat controls self-regulated host plant resistance to insects

J Guo, H Wang, W Guan, Q Guo, J Wang, J Yang… - Nature, 2023 - nature.com
Plants deploy receptor-like kinases and nucleotide-binding leucine-rich repeat receptors to
confer host plant resistance (HPR) to herbivores. These gene-for-gene interactions between …