An industrially feasible approach to overcome the solubility and bioavailability limitations of
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …

Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active
pharmaceutical ingredient (API) and small molecule excipients. The properties of these …

The central composite design is the most commonly used fractional factorial design used in
the response surface model. In this design, the center points are augmented with a group of …

Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on
the market. Microfluidic-based preparation methods stand up as a promising approach with …

Vegetable oil refineries wastewater poses significant challenges to treatment techniques
due to its characteristic fluctuations. In this study, a full factorial design (FFD) was applied to …

Current microparticle (MP) development still strongly relies on the laborious trial-and-error
approach. Herein, we developed a systemic method to evaluate the significance of MP …

Abstract Box–Behnken designs (BBDs) are the very efficient response surface design which
provides information exclusively on the effect of experiment variables and overall …

This research conducts a systematic literature review and case study analysis to compare
the Design of Experiments (DOE) and Active Learning (AL) methods in the context of …

This paper presents an efficient inverse global optimization approach for damage
identification of plate-like structures. In this approach, the damage identification process is …

The multi-attribute method (MAM) based on liquid chromatography (LC)–tandem mass
spectrometry is emerging as a powerful tool to directly monitor multiple product quality …