Objective: To review the role of oxidative stress in two common placental-related disorders
of pregnancy, miscarriage and preeclampsia. Methods: Review of published literature …

Placental explant cultures in vitro are useful for studying tissue functions including cellular
uptake, production and release of secretory components, cell interactions, proliferation …

Biobanks provide an important repository of samples for research purposes. However, for
those samples to reflect the in vivo state, and for experimental reliability and reproducibility …

Human embryonic stem cells (ESCs) readily commit to the trophoblast lineage after
exposure to bone morphogenetic protein-4 (BMP-4) and two small compounds, an activin A …

The use of in vitro tools to study trophoblast differentiation and function is essential to
improve understanding of normal and abnormal placental development. The relative …

Placental apoptosis is increased in vivo in preeclampsia (PE) and intrauterine growth
restriction (IUGR). The cause and pathological implications of this phenomenon are …

This review considers mechanisms by which transfer across the placenta takes place and
how the capacity of the placenta to supply nutrients relates to fetal growth and vice versa …

The syncytiotrophoblast contains aggregates of nuclei termed syncytial knots. Increased
numbers of syncytial knots have been reported in placentae of pregnancies complicated by …

Micro-and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs …

Mammalian pregnancy is an intriguing immunological phenomenon where the
semiallogeneic fetus is not rejected. Tolerance toward the fetus involves a number of …