Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

Multidrug resistance (MDR), defined as the ability of cancer cells to gain resistance to both
conventional and novel chemotherapy agents, is an important barrier in treating …

Purpose: Autologous chimeric antigen receptor T (CAR-T) cell therapy is an effective
treatment for relapsed/refractory acute lymphoblastic leukemia (r/r ALL). However, certain …

GM2 gangliosidoses are a group of pathologies characterized by GM2 ganglioside
accumulation into the lysosome due to mutations on the genes encoding for the β …

In recent years, gene therapy has been raising hopes toward viable treatment strategies for
rare genetic diseases for which there has been almost exclusively supportive treatment. We …

As genome-editing nucleases move toward broader clinical applications, the need to define
the limits of their specificity and efficiency increases. A variety of approaches for nuclease …

The unending outburst of COVID-19 has reinforced the necessity of SARS-CoV-2
identification approaches for the prevention of infection transmission and the proper care of …

Glucagon-like peptide-1 receptor (GLP1R) agonists and dipeptidyl peptidase 4 inhibitors are
widely prescribed diabetes drugs due to their ability to stimulate insulin secretion from …

Carbon dioxide is the major greenhouse gas and regards as the critical issue of global
warming and climate changes. The inconspicuous microalgae are responsible for 40% of …

Gene therapy holds great promise in the treatment of genetic diseases. It is now possible to
make DNA modifications using the CRISPR system. However, a major problem remains: the …