Protein homeostasis or proteostasis is an equilibrium of biosynthetic production, folding and
transport of proteins, and their timely and efficient degradation. Proteostasis is guaranteed …

Previously, we demonstrated that the SCF cyclin F complex directly mediates the poly-
ubiquitylation of TDP-43, raising the question of whether cyclin F can be used to enhance …

Killer meiotic drivers are selfish DNA loci that sabotage the gametes that do not inherit them
from a driver+/driver-heterozygote. These drivers often employ toxic proteins that target …

Protein homeostasis or proteostasis is an equilibrium of biosynthetic production, folding and
transport of proteins, and their timely and efficient degradation. Proteostasis is guaranteed …

During cell cycle progression, hundreds of proteins are subjected to various post-
translational modifications (PTMs) that regulate key events of cellular proliferation. Kinase …

Machado-Joseph disease (MJD) is a genetic form of neurodegeneration that is typically
diagnosed around the fourth decade of life and results in progressive loss of movement …