Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells

A Martí-Rodrigo, F Alegre, ÁB Moragrega… - Gut, 2020 - gut.bmj.com
Objective Liver fibrosis constitutes a major health problem worldwide due to its rapidly
increasing prevalence and the lack of specific and effective treatments. Growing evidence …

Improvement of lipid profile after switching from efavirenz or ritonavir-boosted protease inhibitors to rilpivirine or once-daily integrase inhibitors: results from a large …

L Taramasso, P Tatarelli, E Ricci, G Madeddu… - BMC Infectious …, 2018 - Springer
Background Dyslipidemia represents a significant non-infectious comorbidity among people
living with HIV. The aim of this study is to evaluate the impact on lipid profile of switches from …

Implication of autophagy in the antifibrogenic effect of Rilpivirine: when more is less

F Lucantoni, AM Benedicto, A Gruevska… - Cell Death & …, 2022 - nature.com
As the main extracellular matrix-producing cells, activated hepatic stellate cells (HSC) are
fundamental mediators of liver fibrosis (LF), and understanding their activation/inactivation …

Observational cohort study of rilpivirine (RPV) utilization in Europe

A Cozzi-Lepri, L Peters, A Pelchen-Matthews… - AIDS research and …, 2022 - Springer
Introduction Data on safety and effectiveness of RPV from the real-world setting as well as
comparisons with other NNRTIs such as efavirenz (EFV) remain scarce. Methods …

Usefulness of therapeutic drug monitoring of rilpivirine and its relationship with virologic response and resistance in a cohort of naive and pretreated HIV‐infected …

N Néant, MP Lê, N Bouazza… - British Journal of …, 2020 - Wiley Online Library
Aims The purpose of this study was to assess the antiviral activity of the
rilpivirine/emtricitabine/tenofovir disoproxil fumarate combination and to describe the …

Long-term effectiveness of rilpivirine-based single-tablet regimens in a seven-year, two-center observational cohort of people living with HIV

L Taramasso, S Lo Caputo, L Magnasco… - AIDS Research and …, 2022 - liebertpub.com
Data on the long-term durability of rilpivirine (RPV) are still scarce. A two-center
retrospective study was performed, including all people living with HIV (PLWH) treated with …

Comparison of the efficacy, safety and durability of a switch to co-formulated RPV/TDF-TAF/FTC or DTG/ABC/3TC in virologically-suppressed HIV-1-infected patients …

F Lagi, A Botta, ST Kiros, M Meli, B Borchi… - International Journal of …, 2022 - Elsevier
This study evaluated the efficacy, safety and durability of a switch to co-formulated RPV/TDF-
TAF/FTC (RPV-STR) or DTG/ABC/3TC (DTG-STR) in virologically-suppressed HIV-positive …

Implication of autophagy in the antifibrogenic effect of Rilpivirine: when more is less

L Federico, AM Benedicto, G Aleksandra… - Cell Death and …, 2022 - search.proquest.com
As the main extracellular matrix-producing cells, activated hepatic stellate cells (HSC) are
fundamental mediators of liver fibrosis (LF), and understanding their activation/inactivation …

[HTML][HTML] Efficacy and safety of Efavirenz 400 mg-based regimens switching from 600 mg-based regimens in people living with HIV with virological suppression in …

J Xiao, J Xiao, Y Liu, B Li, L Zhang, J Han… - International Journal of …, 2022 - Elsevier
Background Efavirenz (EFV) 400 mg has been recommended to replace EFV 600 mg. There
are only 200 mg and 600 mg dosage forms of EFV in China. Whether switching from one …

HIV-1 genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan

HC Tsai, IT Chen, SSJ Lee, YS Chen - Infection and Drug …, 2018 - Taylor & Francis
Purpose: Sparse data are available on the prevalence of resistance among HIV-1-infected
patients with virological failure to a single-tablet regimen (STR). This study aimed to …