Application of machine learning in nanotoxicology: a critical review and perspective
Y Zhou, Y Wang, W Peijnenburg… - Environmental …, 2024 - ACS Publications
The massive production and application of nanomaterials (NMs) have raised concerns
about the potential adverse effects of NMs on human health and the environment …
about the potential adverse effects of NMs on human health and the environment …
Physiologically based pharmacokinetic modeling of nanoparticle biodistribution: a review of existing models, simulation software, and data analysis tools
EO Kutumova, IR Akberdin, IN Kiselev… - International Journal of …, 2022 - mdpi.com
Cancer treatment and pharmaceutical development require targeted treatment and less toxic
therapeutic intervention to achieve real progress against this disease. In this scenario …
therapeutic intervention to achieve real progress against this disease. In this scenario …
[HTML][HTML] Easy-MODA: Simplifying standardised registration of scientific simulation workflows through MODA template guidelines powered by the Enalos Cloud …
Modelling Data (MODA) reporting guidelines have been proposed for common terminology
and for recording metadata for physics-based materials modelling and simulations in a CEN …
and for recording metadata for physics-based materials modelling and simulations in a CEN …
[HTML][HTML] In silico assessment of nanoparticle toxicity powered by the Enalos Cloud Platform: Integrating automated machine learning and synthetic data for enhanced …
DD Varsou, PD Kolokathis, M Antoniou… - Computational and …, 2024 - Elsevier
The rapid advance of nanotechnology has led to the development and widespread
application of nanomaterials, raising concerns regarding their potential adverse effects on …
application of nanomaterials, raising concerns regarding their potential adverse effects on …
[HTML][HTML] NanoBioAccumulate: Modelling the uptake and bioaccumulation of nanomaterials in soil and aquatic invertebrates via the Enalos DIAGONAL Cloud Platform
NanoBioAccumulate is a free-to-use web-based tool hosted on the Enalos DIAGONAL
Cloud Platform (https://www. enaloscloud. novamechanics. com/diagonal/pbpk/) that …
Cloud Platform (https://www. enaloscloud. novamechanics. com/diagonal/pbpk/) that …
The nanosafety assessment of ENMs under a dermal exposure scenario: from key molecular events to in silico modeling tools
W Xie, Z Xiong, H Wang, X Liu, H Cui… - Environmental …, 2024 - pubs.rsc.org
While the use of engineered nanomaterials (ENMs) expanding to various applications and
commercial products, public concerns about their potential hazards on exposure to humans …
commercial products, public concerns about their potential hazards on exposure to humans …
Overview of in vitro-in vivo extrapolation approaches for the risk assessment of nanomaterial toxicity
Nanomaterials are increasingly used in many applications due to their enhanced properties.
To ensure their safety for humans and the environment, nanomaterials need to be evaluated …
To ensure their safety for humans and the environment, nanomaterials need to be evaluated …
New Approach Methodologies (NAMs): Rethinking Preclinical Evaluation of Pharmaceuticals and Medical Devices Beyond Animal Models
N Kasoju, S Kripasagari - Animal Models in Research: Principles and …, 2024 - Springer
With the expansion of research and development in pharmaceutical and medical device
sector, the demand for experimental animals is predicted to increase manyfold. However …
sector, the demand for experimental animals is predicted to increase manyfold. However …
Lung Dosimetry Modelling in Nanotoxicology: A Critical Analysis of the State of the Art
W Utembe, N Sanabria - Environmental Sciences Proceedings, 2022 - mdpi.com
The estimation of the dose of inhaled nanomaterials is of fundamental importance in
occupational and environmental health. Indeed, the toxicology and risk assessment of …
occupational and environmental health. Indeed, the toxicology and risk assessment of …