It has been one and a half centuries since Enrico Sertoli published the seminal discovery of
the testicular 'nurse cell', not only a key cell in the testis, but indeed one of the most amazing …

The purpose of this review is to describe the endocrine and local testicular factors that
contribute to the regulation of the blood-testis barrier (BTB), using information gained from in …

Blood-testis barrier (BTB) creates a particular compartment in the seminiferous epithelium.
Contacting Sertoli cell-Sertoli cell plasma membranes possess specialized junction proteins …

Abstract Microplastics (MPs) and nanoplastics (NPs) widely exist in human living
environment and enter the body through water, food chain and breathing. Several studies …

Sertoli cells (SCs) provide structural and nutritional support for developing germ cells.
Normal glucose metabolism of SCs is necessary for spermatogenesis. Melatonin could …

In this study, 24 healthy male sheep were divided into four groups: the control group, Mo
group (45 mg Mo· kg-1· BW), Cd group (1 mg Cd· kg-1· BW), and Mo+ Cd group (45 mg Mo …

This study examined the effects of exposure to lead acetate (PbAc) and/or aluminum trioxide
nanoparticles (Al2O3NPs) on testicular function. Additionally, the probable reproprotective …

Sustaining and maintaining the intricate process of spermatogenesis is liable upon
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …

Leydig cells are the primary source of testosterone or androgen production in male
mammals. The blood–testis barrier (BTB) maintains structural integrity and safeguards germ …

Macrophages are important in the activation of innate immune responses and in a tissue-
specific manner in the maintenance of organ homeostasis. Testicular macrophages (TM) …