The Huisgen 1, 3-dipolar cycloaddition reaction of organic azides and alkynes1, 2 has gained considerable attention in recent years due to the introduction in 2001 of Cu (1) …
The modification of polymers after the successful achievement of a polymerization process represents an important task in macromolecular science. Cycloaddition reactions, among …
GC Tron, T Pirali, RA Billington… - Medicinal research …, 2008 - Wiley Online Library
In recent years, there has been an ever‐increasing need for rapid reactions that meet the three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions …
The investigation of biological processes by chemical methods, commonly referred to as chemical biology, often requires chemical access to biologically relevant macromolecules …
Dipolar cycloaddition reactions can be considered a powerful synthetic tool in the building of heterocyclic rings, with applications in different fields. In this review we focus on the …
The metal catalyzed azide/alkyne 'click'reaction (a variation of the Huisgen 1, 3‐dipolar cycloaddition reaction between terminal acetylenes and azides) has vastly increased in …
Positioned at the C-terminus of many eukaryotic proteins, the glycosylphosphatidylinositol (GPI) anchor is a posttranslational modification that anchors the modified protein in the outer …
This feature article provides a compilation of tools available for preparing well-defined peptide/protein–polymer conjugates, which are defined as hybrid constructs combining (i) a …
L Sun, C Zheng, TJ Webster - International journal of …, 2017 - Taylor & Francis
Over the last several decades, a great number of advances have been made in the area of self-assembled supramolecules for regenerative medicine. Such advances have involved …