RNA molecules are essential for cellular information transfer and gene regulation, and
RNAs have been implicated in many human diseases. Messenger and non-coding RNAs …

The BLAST programs are widely used tools for searching protein and DNA databases for
sequence similarities. For protein comparisons, a variety of definitional, algorithmic and …

The MobiDB database (URL: https://mobidb. org/) is a knowledge base of intrinsically
disordered proteins. MobiDB aggregates disorder annotations derived from the literature …

The arrangement (syntax) of transcription factor (TF) binding motifs is an important part of the
cis-regulatory code, yet remains elusive. We introduce a deep learning model, BPNet, that …

Understanding the genetic regulatory code governing gene expression is an important
challenge in molecular biology. However, how individual coding and non-coding regions of …

Background BLAST is a commonly-used software package for comparing a query sequence
to a database of known sequences; in this study, we focus on protein sequences. Position …

High-affinity nucleic acid ligands for a protein were isolated by a procedure that depends on
alternate cycles of ligand selection from pools of variant sequences and amplification of the …

WebLogo generates sequence logos, graphical representations of the patterns within a
multiple sequence alignment. Sequence logos provide a richer and more precise …

Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify
amino acid substitutions in protein-coding regions. Each substitution has the potential to …

A graphical method is presented for displaying the patterns in a set of aligned sequences.
The characters representing the sequence are stacked on top of each other for each position …