Non-alcoholic fatty liver disease (NAFLD)–pathogenesis, classification, and effect on drug metabolizing enzymes and transporters

E Cobbina, F Akhlaghi - Drug metabolism reviews, 2017 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of liver disorders. It is defined by the
presence of steatosis in more than 5% of hepatocytes with little or no alcohol consumption …

Order out of chaos: assembly of ligand binding sites in heparan sulfate

JD Esko, SB Selleck - Annual review of biochemistry, 2002 - annualreviews.org
▪ Abstract Virtually every cell type in metazoan organisms produces heparan sulfate. These
complex polysaccharides provide docking sites for numerous protein ligands and receptors …

Glacier ice archives nearly 15,000-year-old microbes and phages

ZP Zhong, F Tian, S Roux, MC Gazitúa, NE Solonenko… - Microbiome, 2021 - Springer
Background Glacier ice archives information, including microbiology, that helps reveal
paleoclimate histories and predict future climate change. Though glacier-ice microbes are …

The chemistry and biotransformation of tea constituents

S Sang, JD Lambert, CT Ho, CS Yang - Pharmacological research, 2011 - Elsevier
Tea (Camellia sinensis, Theaceae) is one of the most widely consumed beverages in the
world. The three major types of tea, green tea, oolong tea, and black tea, differ in terms of the …

Sulfur and selenium: the role of oxidation state in protein structure and function

C Jacob, GI Giles, NM Giles… - Angewandte Chemie …, 2003 - Wiley Online Library
Sulfur and selenium occur in proteins as constituents of the amino acids cysteine,
methionine, selenocysteine, and selenomethionine. Recent research underscores that these …

Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities

CJ Omiecinski, JP Vanden Heuvel… - Toxicological …, 2011 - academic.oup.com
To commemorate the 50th anniversary of the Society of Toxicology, this special edition
article reviews the history and current scope of xenobiotic metabolism and transport, with …

Human sulfotransferases and their role in chemical metabolism

N Gamage, A Barnett, N Hempel… - Toxicological …, 2006 - academic.oup.com
Sulfonation is an important reaction in the metabolism of numerous xenobiotics, drugs, and
endogenous compounds. A supergene family of enzymes called sulfotransferases (SULTs) …

Sulfur metabolism and stress defense responses in plants

FR Capaldi, PL Gratão, AR Reis, LW Lima… - Tropical plant …, 2015 - Springer
Sulfur management is an important issue in crop plant nutrition. Sulfur has a role in
fundamental processes such as electron transport, structure and regulation. It is also …

Enzymatic mechanisms of phosphate and sulfate transfer

WW Cleland, AC Hengge - Chemical reviews, 2006 - ACS Publications
Many biological molecules contain phosphate or sulfate, and the enzymatic reactions that
transfer these groups play important roles in metabolism. DNA and RNA are phosphate …

Sulfur metabolism in phototrophic sulfur bacteria

NU Frigaard, C Dahl - Advances in microbial physiology, 2008 - Elsevier
Phototrophic sulfur bacteria are characterized by oxidizing various inorganic sulfur
compounds for use as electron donors in carbon dioxide fixation during anoxygenic …