Developing phage therapy that overcomes the evolution of bacterial resistance

A Oromí-Bosch, JD Antani… - Annual Review of Virology, 2023 - annualreviews.org
The global rise of antibiotic resistance in bacterial pathogens and the waning efficacy of
antibiotics urge consideration of alternative antimicrobial strategies. Phage therapy is a …

Sociobiology of the myxobacteria

GJ Velicer, M Vos - Annual review of microbiology, 2009 - annualreviews.org
Cooperation is integral to much of biological life but can be threatened by selfish
evolutionary strategies. Diverse cooperative traits have evolved among microbes, but …

[HTML][HTML] Decay of infectious SARS-CoV-2 and surrogates in aquatic environments

L Sala-Comorera, LJ Reynolds, NA Martin… - Water Research, 2021 - Elsevier
The introduction of SARS-CoV-2 containing human stool and sewage into water bodies may
raise public health concerns. However, assessment of public health risks by faecally …

Effects of Sequential and Simultaneous Applications of Bacteriophages on Populations of Pseudomonas aeruginosa In Vitro and in Wax Moth Larvae

AR Hall, D De Vos, VP Friman, JP Pirnay… - Applied and …, 2012 - Am Soc Microbiol
Interest in using bacteriophages to treat bacterial infections (phage therapy) is growing, but
there have been few experiments comparing the effects of different treatment strategies on …

Bacteriophage therapy for infections in CF

BK Chan, G Stanley, M Modak, JL Koff… - Pediatric …, 2021 - Wiley Online Library
Pseudomonas aeruginosa and Staphylococcus aureus are bacterial pathogens frequently
associated with pulmonary complications and disease progression in cystic fibrosis (CF) …

The evolution of cheating in viruses

A Leeks, SA West, M Ghoul - Nature Communications, 2021 - nature.com
The success of many viruses depends upon cooperative interactions between viral
genomes. However, whenever cooperation occurs, there is the potential for 'cheats' to …

Notes on recombination and reassortment in multipartite/segmented viruses

A Varsani, P Lefeuvre, P Roumagnac… - Current opinion in virology, 2018 - Elsevier
Highlights•Multipartite and segmented viruses are members of∼ 11% of classified virus
genera.•Segmented viruses with semi-infectious particles have higher propensity to …

Novel approaches to multidrug-resistant infections in cystic fibrosis

TS Murray, G Stanley, JL Koff - Clinics in Chest Medicine, 2022 - chestmed.theclinics.com
Patients with cystic fibrosis (CF) are colonized early in life with bacteria and treated with
repeated cycles of antibiotics. This leads to the emergence of pathogenic chronic multidrug …

What can phages tell us about host‐pathogen coevolution?

JJ Dennehy - International journal of evolutionary biology, 2012 - Wiley Online Library
The outcomes of host‐parasite interactions depend on the coevolutionary forces acting upon
them, but because every host‐parasite relation is enmeshed in a web of biotic and abiotic …

Robustness promotes evolvability of thermotolerance in an RNA virus

RC McBride, CB Ogbunugafor, PE Turner - BMC evolutionary biology, 2008 - Springer
Background The ability for an evolving population to adapt to a novel environment is
achieved through a balance of robustness and evolvability. Robustness is the invariance of …