Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Skip to main content Thank
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The widespread nature of several viruses is greatly credited to their rapidly altering RNA
genomes that enable the infection to persist despite challenges presented by host cells …

What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in
December 2019, was later determined to be coronavirus disease 2019 (COVID-19). The …

Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing
machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3 …

Human history is observing a very strange time fighting an invisible enemy; the novel COVID-
19 coronavirus. Initially observed in the Wuhan province of China, now fastly spreading …

Summary SARS-CoV-2 (previously 2019-nCoV or Wuhan coronavirus) caused an
unprecedented fast-spreading worldwide pandemic. Although currently with a rather low …

In the present work, the succinic acid (SA), L-pyroglutamic acid (L-PGA), N-phenyl-
thioacetamide (N-NPTA), 2-amino-5-chloropyridine hydrogen succinate (ACPS) …

Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved
proteins in living organisms. AHCY catalyzes the reversible break of S …

Over the last twenty years, fluorination on nucleoside has established itself as the most
promising tool to use to get biologically active compounds that could sustain the clinical trial …

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in
recent decades, causing large-scale epidemics in many parts of the world. CHIKV infection …