NAFLD as a driver of chronic kidney disease

CD Byrne, G Targher - Journal of hepatology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

Association of metabolic dysfunction-associated fatty liver disease with kidney disease

TY Wang, RF Wang, ZY Bu, G Targher… - Nature Reviews …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of fat in more
than 5% of hepatocytes in the absence of excessive alcohol consumption and other …

Non-alcoholic fatty liver disease and risk of incident chronic kidney disease: an updated meta-analysis

A Mantovani, G Petracca, G Beatrice, A Csermely… - Gut, 2022 - gut.bmj.com
Objective Studies reported a significant association between non-alcoholic fatty liver
disease (NAFLD) and increased risk of chronic kidney disease (CKD). However, whether …

[HTML][HTML] Adiponectin, leptin, and fatty acids in the maintenance of metabolic homeostasis through adipose tissue crosstalk

JH Stern, JM Rutkowski, PE Scherer - Cell metabolism, 2016 - cell.com
Metabolism research has made tremendous progress over the last several decades in
establishing the adipocyte as a central rheostat in the regulation of systemic nutrient and …

[HTML][HTML] NAFLD: a multisystem disease

CD Byrne, G Targher - Journal of hepatology, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries that is predicted to become also the most frequent indication for liver …

[HTML][HTML] Role of inflammatory response in liver diseases: Therapeutic strategies

JA Del Campo, P Gallego, L Grande - World journal of hepatology, 2018 - ncbi.nlm.nih.gov
Inflammation and tumorigenesis are tightly linked pathways impacting cancer development.
Inflammasomes are key signalling platforms that detect pathogenic microorganisms …

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

QM Anstee, G Targher, CP Day - Nature reviews Gastroenterology & …, 2013 - nature.com
NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …

Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis

G Musso, R Gambino, JH Tabibian, M Ekstedt… - PLoS …, 2014 - journals.plos.org
Background Chronic kidney disease (CKD) is a frequent, under-recognized condition and a
risk factor for renal failure and cardiovascular disease. Increasing evidence connects non …

Human plasma protein N-glycosylation

F Clerc, KR Reiding, BC Jansen, GSM Kammeijer… - Glycoconjugate …, 2016 - Springer
Glycosylation is the most abundant and complex protein modification, and can have a
profound structural and functional effect on the conjugate. The oligosaccharide fraction is …

[PDF][PDF] Histological severity and clinical outcomes of nonalcoholic fatty liver disease in nonobese patients

JCF Leung, TCW Loong, JL Wei, GLH Wong… - …, 2017 - Wiley Online Library
Although nonalcoholic fatty liver disease (NAFLD) is closely linked to obesity, around 10%‐
20% of nonobese Americans and Asians still develop NAFLD. Data on this special group …