Tuberculosis, caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb), is the
leading cause of death from an infectious disease, with a mortality rate of over a million …

Mycobacterium tuberculosis, which is the aetiological agent of tuberculosis, owes much of its
success as a pathogen to its unique cell wall and unusual mechanism of growth, which …

Methods for visualizing protein or nucleic acid motifs have traditionally relied upon residue
frequencies to graphically scale character heights. We describe the pLogo, a motif …

Genomic studies have revealed the presence of Ser/Thr kinases and phosphatases in many
bacterial species, although their physiological roles have largely been unclear. Here we …

During growth and propagation, a bacterial cell enlarges and subsequently divides its
peptidoglycan (PG) sacculus, a continuous mesh‐like layer that encases the cell membrane …

The post-translational modification (PTM) of proteins plays a critical role in the regulation of
a broad range of cellular processes in eukaryotes. Yet their role in governing similar systems …

Protein post‐translational modifications (PTMs) represent important regulatory states that
when combined have been hypothesized to act as molecular codes and to generate a …

N ɛ-Acetylation of lysine residues represents a pivotal post-translational modification used
by both eukaryotes and prokaryotes to modulate diverse biological processes …

Mycobacterium tuberculosis (Mtb) remains an important human pathogen. The Mtb cell
envelope is a critical bacterial structure that contributes to virulence and pathogenicity …

Prokaryotic cell wall biosynthesis is coordinated with cell growth and division, but the
mechanisms regulating this dynamic process remain obscure. Here, we describe a …